| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-50002 |
CA-4948
|
1801344-14-8 |
Emavusertib (CA-4948) is a potent, selective and orally active IRAK4 inhibitor with IC50 of 31.7 nM. |
| PC-45740 |
PF-06650833
|
1817626-54-2 |
PF-06650833 (PF06650833) is a potent and selective IRAK4 inhibitor with IC50 of 0.2 nM. |
| PC-49845 |
GLPG2534
|
2095615-97-5 |
GLPG2534 (GLPG 2534) is a potent, selective IRAK4 inhibitor with therapeutic potential in chronic inflammatory skin diseases. |
| PC-49046 |
ND-2110
|
1388894-17-4 |
ND2110 is a highly selective and bioavailable small molecule IRAK4 inhibitor with IC50 of 7.5 nM, no significant activity against IRAK1 (IC50>2000 nM). |
| PC-38684 |
BAY1830839
|
1931994-80-7 |
BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway. |
| PC-38683 |
Zabedosertib
|
1931994-81-8 |
Zabedosertib (BAY1834845) is a potent, selective IRAK4 inhibitor with IC50 of 3.4 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway. |
| PC-73131 |
HS-243
|
848249-10-5 |
HS-243 (HS243) is a highly potent, super-selective IRAK-1/4 inhibitor with IC50 of 24/20 nM, respectively. |
