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BAY1830839

Chemical Structure : BAY1830839

CAS No.: 1931994-80-7

BAY1830839 (BAY 1830839)

Catalog No.: PC-38684Not For Human Use, Lab Use Only.

BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.

Physicochemical Properties

M.Wt 450.462
Formula C22H25F3N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[2-(3-Hydroxy-3-methylbutyl)-6-(1-hydroxy-1-methylethyl)-2H-indazol-5-yl]-6-(trifluoromethyl)-2-pyridinecarboxamide

References

1. Michael D Wiese et al. Expert Opin Investig Drugs. 2020 May;29(5):475-482.

2. Zheng J, et al. Bioorg Med Chem Lett. 2021 Apr 15;38:127862.

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