Cat. No. |
Product Name |
Information |
PC-49840 |
NPP-669
Antiviral agent
|
NPP-669 (NPP669) is an orally bioavailable cidofovir (CDV) analogue and prodrug, has increased lipophilicity, improved oral absorption, reduced nephrotoxicity, increased cellular uptake, and increased activity against several dsDNA viruses compared to CDV. |
PC-47051 |
JMX0493
Adenoviruse inhibitor
|
JMX0493 is a potent inhibitor of human adenoviruse (HAdV) infection with IC50 of 0.78 uM (HAdV-5), targets HAdV entry pathway and prevents viral particle disassembly and subsequent release from the endosome. |
PC-38784 |
Maribavir
CMV pUL97 inhibitor
|
Maribavir (1263W94, Benzimidavir) is a potent and selective inhibitor of human cytomegalovirus (HCMV) replication with IC50 of 0.13 uM against laboratory strain AD169, and 0.03-0.13 uM against 10 clinical HCMV isolates. |
PC-38414 |
HHV protease inhibitor 43
HHV protease inhibitor
|
HHV protease inhibitor 43 is an irreversible small molecule inhibitor of human herpesvirus (HHV) protease targeting a non-catalytic cysteine (C161) with IC50 of 4 uM (HCMV), exhibits broad-spectrum inhibition of other HHV protease homologs. |
PC-73324 |
Letermovir
CMV inhibitor
|
Letermovir (AIC246) is a potent anti-cytomegalovirus (CMV) compound, exhibits very potent in vitro antiviral activity aginst different HCMV laboratory strains (EC50=3-5 nM), through a specific antiviral mechanism that involves the viral terminase. |
PC-35123 |
CFI02
HCMV inhibitor
|
CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169. |
PC-62054 |
Brincidofovir
Antiviral agent
|
Brincidofovir (CMX 001, Cidofovir HDP) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir that shows activity against all five families of dsDNA viruses that cause human morbidity and mortality, including orthopoxviruses such as variola virus, the cause of human smallpox. |
PC-61947 |
GW 275175X
HCMV inhibitor
|
GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation. |
PC-61946 |
BDCRB
CMV inhibitor
|
BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.. |
PC-61945 |
Tomeglovir
CMV inhibitor
|
Tomeglovir (BAY 384766) is a potent, highly selective, nonnucleoside inhibitor of cytomegalovirus (CMV) replication. |
PC-45259 |
Cidofovir
CMV inhibitor
|
Cidofovir (GS-0504, HPMPC) is the prodrug of cidofovir diphosphate that inhibits cytomegalovirus (CMV) viral replication by selectively inhibiting viral DNA polymerases. |
PC-24684 |
LAVR-289
Poxviruses inhibitor
|
LAVR-289 is a novel acyclic nucleoside phosphonate that effectively inhibits viral replication by targeting a specific domain in the poxvirus DNA polymerase, exhibits antiviral activity against HCMV, vaccinia virus (VV) and HSV-1 (TK-) with EC50 of 21 nM, 50 nM and 8.5 nM respectively. |