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Chemical Structure : JMX0493
Catalog No.: PC-47051Not For Human Use, Lab Use Only.
JMX0493 is a potent inhibitor of human adenoviruse (HAdV) infection with IC50 of 0.78 uM (HAdV-5), targets HAdV entry pathway and prevents viral particle disassembly and subsequent release from the endosome.
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JMX0493 is a potent inhibitor of human adenoviruse (HAdV) infection with IC50 of 0.78 uM (HAdV-5), targets HAdV entry pathway and prevents viral particle disassembly and subsequent release from the endosome.
JMX0493 displayed significant activity in the qPCR assay, inhibiting or delaying HAdV-5 DNA replication by 50% at a concentration of 7.8 uM.
JMX0493 stabilizes HAdV capsid, also shows broad antiviral activity against human cytomegalovirus (HCMV) in a DNA replication assay.
| M.Wt | 267.753 | |
| Formula | C14H18ClNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jimin Xu, et al. Int J Mol Sci. 2021 Feb 5;22(4):1617.
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