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Cat. No. Product Name CAS No. Information
PC-42114

NVP-MELK8a hydrochloride

2096992-20-8 NVP-MELK8a hydrochloride (MELK8a hydrochloride) is a novel potent, and selective MELK inhibitor with IC50 of 2 nM.
PC-44480

OTS-167

1431697-89-0 OTS-167 (OTSSP-167) is a highly potent and selective MELK inhibitor with IC50 of 0.41 nM.
PC-35237

MELK inhibitor 17

2095596-44-2 MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM, >100-fold selectivity over CHK1, CAMKK2, NUAK1 and ERK2.
PC-61764

JW-7-25-1

1222998-57-3 JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM.
PC-61763

HTH-01-091

2000209-42-5 HTH-01-091 is a potent and selective, cell-permeable, ATP-competitive MELK inhibitor with biochemical IC50 of 10.5 nM.
PC-61630

KIN-281

74151-26-1 KIN-281 is a small molecule that inhibits multiple kinases including MELK and the non-receptor tyrosine kinase BMX with IC50 of 1.4 and 1.9 uM, respectively.
PC-70141

Kinase inhibitor C1

133712-17-1 A potent small molecule inhibitor of MELK kinase activity with IC50 of 42 nM.

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