Chemical Structure : OTS167
CAS No.: 1431697-89-0
Catalog No.: PC-44480Not For Human Use, Lab Use Only.
OTSSP167 (OTS167) is a highly potent, selective and orally active MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM.
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5 mg | $88 | In stock | |
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M.Wt | 487.4214 | |
Formula | C25H28Cl2N4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-(6-(3,5-dichloro-4-hydroxyphenyl)-4-(((1r,4r)-4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethanone |
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2. Alachkar H, et al. Oncotarget. 2014 Dec 15;5(23):12371-82.
3. Stefka AT, et al. Blood Cancer J. 2016 Aug 19;6(8):e460.
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