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Cat. No. Product Name Information
PC-72994

TAS4464

NEDD8-activating enzyme inhibitor

TAS4464 (TAS-4464) is a highly potent and selective inhibitor of NEDD8-activating enzyme (NAE) with IC50 of 0.955 nM, >400-fold selectivity over UAE and SAE.
PC-62879

NEDD8 inhibitor M22

NEDD8-activating enzyme inhibitor

NEDD8 inhibitor M22 is a novel, potent, selective reversible NEDD8 activating enzyme (NAE) inhibitor.
PC-60350

ABP-A3

NEDD8-activating enzyme inhibitor

ABP-A3(ABP A3) is an inhibitor of ubiquitin conjugation that targets ubiquitin and Nedd8 E1 enzymes.
PC-45949

Pevonedistat

NEDD8-activating enzyme inhibitor

MLN4924 (Pevonedistat, TAK-924) is an analog of adenosine 5’-monophosphate that potently and selectively inhibits NEDD8-activating enzyme (NAE) with IC50 of 4.7 nM.
PC-42613

MLN-4924 hydrochloride

NEDD8-activating enzyme inhibitor

MLN-4924 (Pevonedistat) hydrochloride is an analog of adenosine 5’-monophosphate that potently and selectively inhibits NEDD8-activating enzyme (NAE) with IC50 of 4.7 nM.

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