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Chemical Structure : ABP-A3
Catalog No.: PC-60350Not For Human Use, Lab Use Only.
ABP-A3(ABP A3) is an inhibitor of ubiquitin conjugation that targets ubiquitin and Nedd8 E1 enzymes.
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ABP-A3(ABP A3) is an inhibitor of ubiquitin conjugation that targets ubiquitin and Nedd8 E1 enzymes.
ABP-A3 inhibits conjugation of ubiquitin to intracellular proteins and prevents the formation of cytoprotective aggresomes.
ABP-A3 induces activation of the unfolded protein response (UPR) and apoptosis, displays IC50 of 2.5 uM in cell viability assays in A549 cells.
| M.Wt | 446.438 | |
| Formula | C18H18N6O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. An H, et al. Chem Sci. 2015 Sep 1;6(9):5235-5245.
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