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Cat. No. Product Name CAS No. Information
PC-63122

YKL 06-061

2172617-15-9 YKL 06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 of 6.56/1.77/20.5 nM for SIK1/2/3, respectively.
PC-61766

ARN-3236

1613710-01-2 ARN-3236 is a novel potent, selective, and orally active SIK2 inhibitor with IC50 of <1 nM.
PC-42327

YKL-05-099

1936529-65-5 YKL-05-099 (YKL 05-099) is a novel potent, selective pan-SIK inhibitor with IC50 of 10, 40 and 30 nM for SIK1, 2 and 3, respectively.
PC-49563

SK-124

2760404-50-8 SK-124 (SK124) is a potent, selective, orally active SIK2/SIK3 inhibitor with IC50 of 8.8/11.3 nM in cell-based NanoBRET assays, 15-fold selectivity versus SIK1.
PC-72723

MRIA9

2750707-05-0 MRIA9 is a potent, selective dual SIK/PAK inhibitor, inhibits SIK1/2/3 with cellular IC50 of 586/180/127 nM, respectively.
PC-63124

rac Pterosin B

60657-37-6 rac Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.
PC-63123

Pterosin B

34175-96-7 Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.

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