Constitutive androstane receptor (CAR) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofConstitutive androstane receptor (CAR) Constitutive androstane receptor (CAR)

Cat. No.	Product Name	Information
PC-49718	TCPOBOP CAR agonist	TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.
PC-49717	S07662 CAR inhibitor	S07662 is a human constitutive androstane receptor (CAR, NR1I3) inverse agonist with IC50 of 0.7 uM, strongly inhibits human CAR activity via recruitment of NR corepressors and to attenuate inducer-elicited CYP2B6 expression in human primary hepatocytes.
PC-49716	DL5050 CAR agonist	DL5050 (DL 5050) is a potent selective agonist of human constitutive androstane receptor (CAR) with EC50 of 0.37 uM in cell-based luciferase reporter assays (Emax=3.8).
PC-49715	CITCO CAR agonist	CITCO is a potent, selective agonist of orphan nuclear constitutive androstane receptor (CAR) with EC50 of 49 nM (human CAR) in CAR/SRC-1 FRET assays.
PC-49714	DL7076 CAR/Nrf2 activator	DL7076 (CN06) is a small molecule dual activator of the constitutive androstane receptor (CAR, NR1I3) and nuclear factor erythroid 2-related factor 2 (Nrf2) with EC50 of 8.85 and 0.72 uM, respectively.

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