You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-Constitutive androstane receptor (CAR)-TCPOBOP
TCPOBOP

Chemical Structure : TCPOBOP

CAS No.: 76150-91-9

TCPOBOP (CAR agonist)

Catalog No.: PC-49718Not For Human Use, Lab Use Only.

TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.

Packing Price Stock Quantity
10 mg $78 In stock
25 mg $128 In stock
50 mg $198 In stock
100 mg $298 In stock
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.
TCPOBOP competes directly for occupancy of the CAR LBD.
TCPOBOP enhances CAR interaction with the coactivator SRC-1 in vivo and in vitro.

Physicochemical Properties

M.Wt 402.05
Formula C16H8Cl4N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,4-bis((3,5-dichloropyridin-2-yl)oxy)benzene

References

1. Wei P, et al. Nature. 2000 Oct 19;407(6806):920-3.

2. Tzameli I, et al. Mol Cell Biol. 2000 May;20(9):2951-8.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: