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Chemical Structure : TCPOBOP
CAS No.: 76150-91-9
Catalog No.: PC-49718Not For Human Use, Lab Use Only.
TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.
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|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $298 | In stock | |
| 250 mg | Get quote |
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TCPOBOP is a phenobarbital-like class of CYP-inducing agent and agonist ligand for constitutive androstane receptor (CAR) with EC50 of 20 nM.
TCPOBOP competes directly for occupancy of the CAR LBD.
TCPOBOP enhances CAR interaction with the coactivator SRC-1 in vivo and in vitro.
| M.Wt | 402.05 | |
| Formula | C16H8Cl4N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,4-bis((3,5-dichloropyridin-2-yl)oxy)benzene |
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1. Wei P, et al. Nature. 2000 Oct 19;407(6806):920-3.
2. Tzameli I, et al. Mol Cell Biol. 2000 May;20(9):2951-8.
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