| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-63031 |
KU-0060648
|
881375-00-4 |
KU-006064 is a potent, dual inhibitor of DNA-PK (IC50=8.6 nM) and PI3K (IC50=4/0.5/0.1 nM for PI3Kα/β/δ). |
| PC-61389 |
Nedisertib
|
1637542-33-6 |
Nedisertib (M3814, MSC2490484A) is a highly potent, selective, orally bioavailable inhibitor of DNA-PK. |
| PC-20171 |
Ku-DBi 245
|
2161403-77-4 |
Ku-DBi 245 is a novel DNA-PK inhibitor with a unique mechanism of action, blocking the Ku 70/80 heterodimer interaction with DNA. |
| PC-73106 |
AZD7648
|
2230820-11-6 |
AZD7648 (AZD-7648) is a potent, selective inhibitor of DNA-PK catalytic subunit (DNA-PKcs) with IC50 of 0.6 nM. |
| PC-72056 |
BAY-8400
|
|
BAY-8400 (BAY8400) is a highly potent, selective inhibitor of DNA-PK with biochemical IC50 of 81 nM, cellular IC50 of 69 nM (γH2AX in HT-144). |
| PC-72041 |
NU5455
|
1257235-99-6 |
NU5455 (NU-5455) is a potent, highly selective, oral inhibitor of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) activity with IC50 of 8.2 nM. |
| PC-43460 |
PIK-75
|
372196-77-5 |
PIK-75 is a potent, isoform-selective p110α inhibitor with IC50 of 0.3 nM, displays >100-fold selectivity over p110β, p110δ and PI3K C2b. |
