| Cat. No. |
Product Name |
Information |
| PC-61389 |
M3814
DNA-PK inhibitor
|
M3814 (Nedisertib, Peposertib, MSC2490484A) is a highly potent, selective, ATP-competitive and orally bioavailable inhibitor of DNA-PK with IC50 of 0.6 nM (10 uM ATP). |
| PC-70103 |
NU-7163
DNA-PK inhibitor
|
NU-7163 is a poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM. |
| PC-45615 |
Compound 401
DNA-PK inhibitor
|
Compound 401 is a synthetic inhibitor of DNA-PK with IC50 of 0.28 uM, also inhibits mTOR (IC50=5.3 uM). |
| PC-42782 |
NU7441
DNA-PK inhibitor
|
NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor (IC50=14 nM). |
| PC-23583 |
Ku-DBi 3392
Ku-DNA inhibitor
|
Ku-DBi 3392 (GL-3392) is a small molecule Ku-DNA binding inhibitor with IC50 of 2.4 uM, shows direct interaction with Ku70-Ku80 with MST Kd of 2.1 uM, exhibits IC50 of 0.77 uM for DNA-PK. |
| PC-23022 |
DA-143
DNA-PKcs inhibitor
|
DA-143 is a potent, selective inhibitor of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) with IC50 of 2.5 nM. |
| PC-22698 |
DNA-PK inhibitor 78
DNA-PK inhibitor
|
DNA-PK inhibitor 78 is a potent, selective DNA-PK inhibitor with IC50 of 7.95 nM, >200-fold selective over PI3Kα and >800-fold over other PI3Ks and mTOR. |
| PC-22675 |
BR101801
PI3Kγ/δ and DNA-PK inhibitor
|
BR101801 is a triple inhibitor of PI3Kγ/δ and DNA-PK, sensitizes radiation-induced DNA damage in various human solid cancer cells. |
| PC-21129 |
ZL-2201 mesylate
DNA-PK inhibitor
|
ZL-2201 mesylate (ZL2201) is a highly potent, selective and orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 of 1.1 nM. |
| PC-21128 |
ZL-2201
DNA-PK inhibitor
|
ZL-2201 (ZL2201) is a highly potent, selective and orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 of 1.1 nM. |
