| Cat. No. |
Product Name |
Information |
| PC-21129 |
ZL-2201 mesylate
DNA-PK inhibitor
|
ZL-2201 mesylate (ZL2201) is a highly potent, selective and orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 of 1.1 nM. |
| PC-21128 |
ZL-2201
DNA-PK inhibitor
|
ZL-2201 (ZL2201) is a highly potent, selective and orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 of 1.1 nM. |
| PC-20221 |
SN38023
DNA-PK inhibitor
|
SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells. |
| PC-20171 |
Ku-DBi 245
DNA-PK inhibitor
|
Ku-DBi 245 is a novel DNA-PK inhibitor with a unique mechanism of action, blocking the Ku 70/80 heterodimer interaction with DNA. |
| PC-72056 |
BAY-8400
DNA-PK inhibitor
|
BAY-8400 (BAY8400) is a highly potent, selective inhibitor of DNA-PK with biochemical IC50 of 81 nM, cellular IC50 of 69 nM (γH2AX in HT-144). |
| PC-72041 |
NU5455
DNA-PK inhibitor
|
NU5455 (NU-5455) is a potent, highly selective, oral inhibitor of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) activity with IC50 of 8.2 nM. |
