| Cat. No. |
Product Name |
Information |
| PC-62995 |
IC 87361
DNA-PK inhibitor
|
IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β. |
| PC-61971 |
VX-984
DNA-PK inhibitor
|
VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members. |
| PC-61970 |
SU-11752
DNA-PK inhibitor
|
SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells. |
| PC-61389 |
Peposertib
DNA-PK inhibitor
|
Peposertib (M3814, Nedisertib, MSC2490484A) is a highly potent, selective, ATP-competitive and orally bioavailable inhibitor of DNA-PK with IC50 of 0.6 nM (10 uM ATP). |
| PC-70103 |
NU-7163
DNA-PK inhibitor
|
NU-7163 is a poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM. |
| PC-45615 |
Compound 401
DNA-PK inhibitor
|
Compound 401 is a synthetic inhibitor of DNA-PK with IC50 of 0.28 uM, also inhibits mTOR (IC50=5.3 uM). |
| PC-42782 |
NU7441
DNA-PK inhibitor
|
NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor (IC50=14 nM). |
| PC-23701 |
NU7026
DNA-PK inhibitor
|
NU7026 is a potent, selective inhibitor of DNA repair enzyme DNA-dependent protein kinase (DNA-PK) with IC50 of 0.23 uM. |
| PC-22698 |
DNA-PK inhibitor 78
DNA-PK inhibitor
|
DNA-PK inhibitor 78 is a potent, selective DNA-PK inhibitor with IC50 of 7.95 nM, >200-fold selective over PI3Kα and >800-fold over other PI3Ks and mTOR. |
| PC-21129 |
ZL-2201 mesylate
DNA-PK inhibitor
|
ZL-2201 mesylate (ZL2201) is a highly potent, selective and orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 of 1.1 nM. |
| PC-21128 |
ZL-2201
DNA-PK inhibitor
|
ZL-2201 (ZL2201) is a highly potent, selective and orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 of 1.1 nM. |
