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Chemical Structure : NU-7163
Catalog No.: PC-70103Not For Human Use, Lab Use Only.
A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM.
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A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM; exhibits selectivity for DNA-PK versus related enzymes ATM, ATR, mTOR, and p110α; sensitizes the HeLa cells to the cytotoxic effects of ionizing radiation in vitro.
| M.Wt | 295.338 | |
| Formula | C18H17NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Griffin RJ, et al. J Med Chem. 2005 Jan 27;48(2):569-85.
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