| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-73319 |
NPX-800
|
1693734-80-3 |
NPX-800 is a potent, selective, oral heat shock factor 1 (HSF1) pathway inhibitor. |
| PC-72710 |
PU-H71
|
873436-91-0 |
PU-H71 (Zelavespib, NSC 750424) is a potent and selective inhibitor of Hsp90 (Heat shock protein 90) with IC50 of 51 nM in MDA-MB-468 cells. |
| PC-72570 |
Hsp90α-IN-12h
|
2765823-81-0 |
Hsp90α-IN-12h is the first Hsp90α-selective inhibitor with IC50 of 460 nM, exhibit 48-fold selectivity versus other Hsp90 isoforms. |
| PC-72068 |
DTHIB
|
897326-30-6 |
DTHIB (Direct Targeted HSF1 InhiBitor, SISU-102) is a specific small molecule HSF1 inhibitor with Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). |
| PC-35293 |
KBU2046
|
1143863-69-7 |
KBU2046 (KBU-2046) is a highly selective inhibitor of metastasis, binds to and stabilizes CDC37/HSP90β heterocomplexes. |
| PC-63191 |
HSP27 inhibitor J2
|
2133499-85-9 |
HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells. |
| PC-62492 |
JG-98
|
1456551-16-8 |
JG-98 is an allosteric Hsp70 inhibitor, displays >3-fold more active, greater stability than MKT-077 against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50 of 0.4 uM and 0.7 uM, respectively). |
