| Cat. No. |
Product Name |
Information |
| PC-42156 |
HA-15
GRP78 inhibitor
|
HA-15 is a specifc inhibitor of the chaperone BiP (Binding immunoglobulin protein, GRP78 or HSPA5) that displays anti-cancerous activity on melanoma cells, including BRAF resistance melanoma cells. |
| PC-42278 |
KRIBB11
HSF1 inhibitor
|
KRIBB11 is a small molecule heat shock factor 1 (HSF1) inhibitor with IC50 of 1.2 uM. |
| PC-42459 |
BIIB021
HSP90 inhibitor
|
BIIB021 (CNF2024) is a potent, selective, orally available HSP90 inhibitor with Ki of 1.7 nM for Hsp90α. |
| PC-42839 |
Alvespimycin hydrochloride
HSP90 inhibitor
|
Alvespimycin hydrochloride (17-DMAG) is a potent, orally bioavailable Hsp90 inhibitor with binding EC50 of 62 nM. |
| PC-42558 |
Alvespimycin
HSP90 inhibitor
|
Alvespimycin (17-DMAG) is a potent, orally bioavailable Hsp90 inhibitor with binding EC50 of 62 nM. |
| PC-42458 |
17-AAG hydrochloride
HSP90 inhibitor
|
17-AAG hydrochloride (Tanespimycin hydrochloride) is a potent Hsp90 inhibitor with IC50 of 5 nM in cell-free assays. |
| PC-42457 |
17-AAG
HSP90 inhibitor
|
17-AAG (Tanespimycin) is a potent Hsp90 inhibitor with IC50 of 5 nM in cell-free assays. |
| PC-42747 |
VER-155008
Hsp70 inhibitor
|
VER-155008 (VER155008) is a potent Hsp70 family (Hsc70/Hsp7/Grp78) inhibitor with Kd of 80 nM for Grp78. |
| PC-42416 |
TRC051384
HSP70 inducer, HSF1 activator
|
TRC051384 is a potent heat shock protein 70 (HSP70) inducer, involves HSF1 activation. |
| PC-42748 |
NVP-BEP800
Hsp90 inhibitor
|
NVP-BEP800 (VER-82576) is a potent and selective HSP90 inhibitor with IC50 of 58 nM for HSP90β. |
| PC-42461 |
NVP-AUY922
HSP90 inhibitor
|
NVP-AUY922 (Luminespib, AUY922) is a potent and selective HSP90 inhibitor with IC50 of 21 and 7.8 nM for HSP90β and HSP90α, respectively. |
| PC-45521 |
PU-WS13
Grp94 inhibitor
|
PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM. |
