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You are here:Home-Chemical Inhibitors & Agonists-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-PU-WS13
PU-WS13

Chemical Structure : PU-WS13

CAS No.: 1454619-14-7

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PU-WS13 (PU-WS-13)

Catalog No.: PC-45521Not For Human Use, Lab Use Only.

PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM.

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10 mg $158 In stock
25 mg $278 In stock
50 mg $458 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM.
PU-WS13 shows >35 fold selectivity over other four HSP90 paralogs, Hsp90α, Hsp90β and Trap-1 (IC50> 7 uM).

Physicochemical Properties

M.Wt 411.3519
Formula C17H20Cl2N6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 40 mg/mL
Chemical Name/SMILES

9H-Purine-9-propanamine, 6-amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-

References

1. Patel PD, et al. Nat Chem Biol. 2013 Nov;9(11):677-84.

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