PU-WS13 |CAS:1454619-14-7 Probechem Biochemicals

Chemical Structure : PU-WS13

CAS No.: 1454619-14-7

PU-WS13 (PU-WS-13)

Catalog No.: PC-45521Not For Human Use, Lab Use Only.

PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM.

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25 mg	$278	In stock
50 mg	$458	In stock
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Biological Activity

PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM.
PU-WS13 shows >35 fold selectivity over other four HSP90 paralogs, Hsp90α, Hsp90β and Trap-1 (IC50> 7 uM).

Physicochemical Properties

M.Wt	411.3519
Formula	C17H20Cl2N6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 40 mg/mL
Chemical Name/SMILES	9H-Purine-9-propanamine, 6-amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-

References

1. Patel PD, et al. Nat Chem Biol. 2013 Nov;9(11):677-84.

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PU-WS13 (PU-WS-13)

Biological Activity

Physicochemical Properties

References

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