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Cat. No. Product Name CAS No. Information
PC-73319

NPX-800

1693734-80-3 NPX-800 is a potent, selective, oral heat shock factor 1 (HSF1) pathway inhibitor.
PC-72710

PU-H71

873436-91-0 PU-H71 (Zelavespib, NSC 750424) is a potent and selective inhibitor of Hsp90 (Heat shock protein 90) with IC50 of 51 nM in MDA-MB-468 cells.
PC-35293

KBU2046

1143863-69-7 KBU2046 (KBU-2046) is a highly selective inhibitor of metastasis, binds to and stabilizes CDC37/HSP90β heterocomplexes.
PC-63191

HSP27 inhibitor J2

2133499-85-9 HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells.
PC-62492

JG-98

1456551-16-8 JG-98 is an allosteric Hsp70 inhibitor, displays >3-fold more active, greater stability than MKT-077 against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50 of 0.4 uM and 0.7 uM, respectively).
PC-61958

TAS-116

1260533-36-5 TAS-116 (Pimitespib, TAS116) is a novel potent, selective, orally available HSP90α/β inhibitor with Ki of 34.7, 21.3, >50,000, and >50,000 nM for HSP90α, HSP90β, GRP94, and TRAP1, respectively.
PC-61250

KW-2478

819812-18-5 KW-2478 (KW2478) is a novel potent Hsp90 inhibitor with IC50 of 3.8 nM (Hsp90α), exhibits antitumor activities both in vitro and in vivo.

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