| Cat. No. |
Product Name |
Information |
| PC-23389 |
SLV320
A1AR antagonist
|
Derenofylline (SLV320) is a potent, selective and orally active adenosine A1 receptor (A1AR) antagonist with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. |
| PC-22840 |
DPCPX
A1AR antagonist
|
DPCPX (PD116948) is a highly potent and selective adenosine A1 receptor antagonist with Ki of 0.46 nM, >500-fold selective over A2 receptor. |
| PC-22193 |
Piclidenoson
A3AR agonist
|
Piclidenoson (IB-MECA, CF101) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist, shows antiproliferative effect and induces apoptosis in multiple cancer cell types like melanoma, leukemia. |
| PC-22013 |
CVT-6694
A2BR antagonist
|
CVT-6694 (CVT6694) is a highly potent, selective A2B adenosine receptor antagonist with Ki of 7 nM (hA2B), >700-fold selective over human A1, A2A and A3 receptors. |
| PC-21513 |
TRR469
A1AR modulator
|
TRR469 is a potent, selective adenosine A1 receptor (A1AR) positive allosteric modulator with pKb of 5.36, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. |
| PC-21512 |
VCP171
A1AR modulator
|
VCP171 is a selective adenosine A1 receptor (A1AR) positive allosteric modulator (PAM), inhibits eEPSC amplitude of nerve-injury versus control animals in both lamina I and lamina II neurons. |
| PC-21510 |
MRS7935
A1AR modulator
|
MRS7935 is a potent, selective positive allosteric modulator (PAM) of A1 adenosine receptor (A1AR) with EC50 of 1.43 uM. |
| PC-20642 |
I-ABOPX
A3AR antagonist
|
I-ABOPX is a potent, selective A3 adenosine receptor antagonist with high affinity for both the ovine (Ki=3 nM) and human (Ki=19 nM) A3 receptors. |
| PC-20640 |
QAF-805
A2BR antagonist
|
QAF-805 (QAF805) is a potent, dual adenosine-A2B receptor and adenosine-A3 receptor antagonist with Ki of 3.4 nM (A2B). |
| PC-20639 |
KF26777
A3AR antagonist
|
KF-26777 (KF26777) is a potent and selective adenosine A3 receptor antagonist with Ki of 0.2 nM (human A3 receptor). |
| PC-20638 |
LAS101057
A2BR antagonist
|
LAS101057 (LAS 101057) is a potent, selective, and orally efficacious A2B adenosine receptor antagonist with Ki of 24 nM (human A2B). |
| PC-20546 |
PSB-1115
A2B antagonist
|
PSB-1115 (PSB1115) is a potent, selective adenosine A2B receptor antagonist with binding Ki of 53.4 nM (recombinant human A2B receptor), 40- and 400-fold selectivity over A1 and A2A receptors. |
