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Chemical Structure : I-ABOPX
Catalog No.: PC-20642Not For Human Use, Lab Use Only.
I-ABOPX is a potent, selective A3 adenosine receptor antagonist with high affinity for both the ovine (Ki=3 nM) and human (Ki=19 nM) A3 receptors.
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I-ABOPX is a potent, selective A3 adenosine receptor antagonist with high affinity for both the ovine (Ki=3 nM) and human (Ki=19 nM) A3 receptors.
I-ABOPX (10 and 40 mg/kg i.v) blocked dose-dependently and surmountable the hypotensive response to APNEA in rats.
| M.Wt | 575.36 | |
| Formula | C23H22IN5O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fozard JR, et al. Eur J Pharmacol. 1994 Feb 3;252(2):R5-6.
2. Salvatore CA, et al. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10365-9.
3. Linden J, et al. Mol Pharmacol. 1993 Sep;44(3):524-32.
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