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Cat. No. Product Name Information
PC-20899

NuP-3

MAPK13 inhibitor

NuP-3 is a potent, selective MAPK13 and MAPK14 inhibitor with IC50 of 7 and 14 nM, respectively.
PC-49582

DCZ19931

Multikinase inhibitor

DCZ19931 is a novel multi-targeting kinase inhibitor, exhibits anti-angiogenic effects in vitro and inhibits ocular neovascularization in vivo.
PC-73415

Emprumapimod

p38 MAPK inhibitor

Emprumapimod (PF-07265803) is a potent, selective and orally bioavailable inhibitor of p38 MAPK, inhibits LPS-induced IL-6 production in RPMI-8226 cells with IC50 of 0.1 nM.
PC-72610

ARRY-371797

p38α inhibitor

ARRY-371797 (ARRY-797) is a potent, selective, oral p38α inhibitor with IC50 of <5 nM, directly inhibits LPS-induced IL-6 production from RPMI-8226 with IC50 of 0.1 nM.
PC-63564

BMS-751324

p38α MAPK inhibitor

BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM.
PC-63408

RV1088

p38 MAPK inhibitor

RV1088 is a potent narrow spectrum kinase inhibitor that target p38, c-Src, Syk or JAK individually, dose-dependently reduces TNF-α levels in LPS-activated macrophages with IC50 of 0.63 nM.
PC-63395

JNJ-49095397

p38 MAPK inhibitor

JNJ-49095397 (RV-568) is a specific narrow-spectrum kinase inhibitor that inhibits a selected set of kinases involved in COPD inflammation with IC50 of 5, 40 and 52 nM for p38α, p38γ and HCK, respectively.
PC-63284

AZD-7624

p38α MAPK inhibitor

AZD-7624 (AZD7624) is a potent, selective, inhaled p38α MAPK inhibitor with pIC50 of 10.0, displays 15-fold selectivity for p38α over p38β MAPK and >10,000-fold selectivity over p38γ and p38δ MAPK.
PC-43421

LY2228820 dimesylate

p38 MAPK inhibitor

LY2228820 dimesylate (Ralimetinib) is a potent, selective, orally available inhibitor p38 MAPK with IC50 of 5.3 and 3.2 nM for p38α and p38β, respectively.
PC-43250

p38 MAPK-IN-4

p38 MAPK inhibitor

p38 MAPK-IN-4 is a potent and selective inhibitor of p38 MAPK with IC50 of 68 nM for p38α, inhibits LPS-induced TNFα release in THP-1 cells with IC50 of 187 nM.
PC-43080

SKF-86002

p38 MAPK inhibitor

SKF-86002 is a potent inhibitor of p38 MAPK with IC50 of 0.5-1 uM, inhibits LPS-induced IL-1 and TNF-α production in human monocyte with IC50 of 1 uM.
PC-42805

SD0006

p38α inhibitor

SD0006 (SD-0006, SD-06) is a potent, selective, ATP-competitive and orally bioavailable p38α inhibitor with Ki of 61 nM.

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