| Cat. No. |
Product Name |
Information |
| PC-72610 |
ARRY-371797
|
ARRY-371797 (ARRY371797) is a potent, selective, oral p38α inhibitor with IC50 of <5 nM, directly inhibits LPS-induced IL-6 production from RPMI-8226 with IC50 of 0.1 nM. |
| PC-60627 |
RWJ 67657
|
RWJ 67657 is a potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-α and IL-1β by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively. |
| PC-60434 |
MW-150
|
MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. |
| PC-42491 |
SB 203580
|
SB 203580 (Adezmapimod, RWJ 64809) is a specific p38 MAPK inhibitor with IC50 of 0.6 uM. |
| PC-42564 |
Losmapimod
|
Losmapimod (GSK-AHAB, GW856553X, SB856553) is a selective, potent, orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. |
| PC-42512 |
SB 202190
|
SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively. |
| PC-42526 |
VX-745
|
A potent and selective p38α kinase inhibitor with IC50 of 9 nM. |
