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Cat. No. Product Name Information
PC-72610

ARRY-371797

ARRY-371797 (ARRY371797) is a potent, selective, oral p38α inhibitor with IC50 of <5 nM, directly inhibits LPS-induced IL-6 production from RPMI-8226 with IC50 of 0.1 nM.
PC-60627

RWJ 67657

RWJ 67657 is a potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-α and IL-1β by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively.
PC-60434

MW-150

MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
PC-42491

SB 203580

SB 203580 (Adezmapimod, RWJ 64809) is a specific p38 MAPK inhibitor with IC50 of 0.6 uM.
PC-42564

Losmapimod

Losmapimod (GSK-AHAB, GW856553X, SB856553) is a selective, potent, orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively.
PC-42512

SB 202190

SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively.
PC-42526

VX-745

A potent and selective p38α kinase inhibitor with IC50 of 9 nM.

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