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Cat. No. Product Name CAS No. Information
PC-60627

RWJ 67657

215303-72-3 RWJ 67657 is a potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-α and IL-1β by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively.
PC-60434

MW-150

1628502-91-9 MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
PC-42491

SB 203580

152121-47-6 SB 203580 (Adezmapimod, RWJ 64809) is a specific p38 MAPK inhibitor with IC50 of 0.6 uM.
PC-42564

Losmapimod

585543-15-3 Losmapimod (GSK-AHAB, GW856553X, SB856553) is a selective, potent, orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively.
PC-42512

SB 202190

152121-30-7 SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively.
PC-42526

VX-745

209410-46-8 A potent and selective p38α kinase inhibitor with IC50 of 9 nM.
PC-49694

VCP979

VCP979 (VCP-979) is a novel selective small molecule p38 MAPK inhibitor with a significantly greater affinity for the active form of p38 MAPK, has significant anti-fibrotic effects in vitro and in vivo.

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