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Cat. No. Product Name Information
PC-42805

SD0006

p38α inhibitor

SD0006 (SD-0006, SD-06) is a potent, selective, ATP-competitive and orally bioavailable p38α inhibitor with Ki of 61 nM.
PC-63103

PF-03715455

p38α inhibitor

PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM.
PC-63000

AW-814141

p38 MAPK inhibitor

AW-814141 (AW814141) is a potent, selective and orally active inhibitor of p38 MAP kinase with IC50 of 100 nM/158 nM for p38α/p38β.
PC-62782

MW181 hydrochloride

p38α inhibitor

MW181 hydrochloride is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ.
PC-62781

MW181

p38α inhibitor

MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ.
PC-62614

NJK14047

p38 MAPK inhibitor

NJK14047 is a novel potent, selective p38 MAPK inhibitor with IC50 of 27 nM against p38α, suppresses RSV and influenza A virus replication by inhibiting virus-induced p38 MAPK activation.
PC-62439

AMG-548

p38α inhibitor

AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and >5,000-fold selectivity over p38γ and p38δ.
PC-61210

SC-806

p38 MAPK inhibitor

SC-806 is a potent, orally active p38 MAPK inhibitor with IC50 of 50 nM, significantly decreases incidence of arthritis in mouse collagen-induced arthritis.
PC-61001

AS1940477

p38α/β inhibitor

AS1940477 is a potent, selective, orally active p38α/p38β inhibitor with IC50 of 11.2/36.5 nM respectively, with no effect on p38γ and δ isoforms (IC50>1 uM).
PC-60627

RWJ 67657

p38 MAPK inhibitor

RWJ 67657 (JNJ 3026582) is a potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-α and IL-1β by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively.
PC-60434

MW-150

p38α inhibitor

MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
PC-60432

MW-150 hydrochloride

p38α inhibitor

MW-150 hydrochloride is a potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.

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