| Cat. No. |
Product Name |
Information |
| PC-63103 |
PF-03715455
p38α inhibitor
|
PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM. |
| PC-63000 |
AW-814141
p38 MAPK inhibitor
|
AW-814141 (AW814141) is a potent, selective and orally active inhibitor of p38 MAP kinase with IC50 of 100 nM/158 nM for p38α/p38β. |
| PC-62781 |
MW181
p38α inhibitor
|
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
| PC-62614 |
NJK14047
p38 MAPK inhibitor
|
NJK14047 is a novel potent, selective p38 MAPK inhibitor with IC50 of 27 nM against p38α, suppresses RSV and influenza A virus replication by inhibiting virus-induced p38 MAPK activation. |
| PC-62439 |
AMG-548
p38α inhibitor
|
AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and >5,000-fold selectivity over p38γ and p38δ. |
| PC-61210 |
SC-806
p38 MAPK inhibitor
|
SC-806 is a potent, orally active p38 MAPK inhibitor with IC50 of 50 nM, significantly decreases incidence of arthritis in mouse collagen-induced arthritis. |
| PC-61001 |
AS1940477
p38α/β inhibitor
|
AS1940477 is a potent, selective, orally active p38α/p38β inhibitor with IC50 of 11.2/36.5 nM respectively, with no effect on p38γ and δ isoforms (IC50>1 uM). |
| PC-60627 |
RWJ 67657
p38 MAPK inhibitor
|
RWJ 67657 (JNJ 3026582) is a potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-α and IL-1β by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively. |
| PC-60434 |
MW-150
p38α inhibitor
|
MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. |
| PC-60432 |
MW-150 hydrochloride
p38α inhibitor
|
MW-150 hydrochloride is a potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. |
| PC-45059 |
Acumapimod
p38 MAPK inhibitor
|
An orally active, potent p38 MAPK inhibitor that potently inhibits ex vivo LPS‐induced TNFα secretion with an IC50 of 44 ng/mL (115 nM). |
| PC-42491 |
SB203580
p38 MAPK inhibitor
|
SB203580 (Adezmapimod, RWJ 64809) is a specific p38 MAPK inhibitor with IC50 of 0.6 uM. |
