| Cat. No. |
Product Name |
Information |
| PC-42564 |
Losmapimod
p38 MAPK inhibitor
|
Losmapimod (GSK-AHAB, GW856553X, SB856553) is a selective, potent, orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. |
| PC-45452 |
SB-242235
p38 MAPK inhibitor
|
SB-242235 is a selective p38 MAPK inhibitor, inhibits IL-1 beta induction of p38 MAPK in primary human chondrocytes with IC50 of 1 uM. |
| PC-42563 |
VX-702
p38 MAPK inhibitor
|
VX-702 is a potent, selective, second generation p38 MAPK inhibitor with IC50 of 4-20 nM for p38α. |
| PC-42565 |
Pamapimod
p38α MAPK inhibitor
|
Pamapimod (Ro4402257; R1503) is a potent, selective, orally bioavailable p38α MAPK inhibitor with Kd of 0.2 nM. |
| PC-42803 |
SB 239063
p38 MAPK inhibitor
|
SB 239063 is a potent, selective, orally available p38 MAPK inhibitor with IC50 of 44 nM for both p38α and p38β. |
| PC-42599 |
TAK-715
p38α inhibitor
|
TAK-715 is a potent, selective, orally active p38α MAPK inhibitor with IC50 of 7.1 nM. |
| PC-42566 |
SCIO-469
p38α MAPK inhibitor
|
Talmapimod (SCIO469) is a potent, selective p38α MAPK inhibitor with IC50 of 9 nM. |
| PC-42662 |
PD 169316
p38 MAPK inhibitor
|
PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM. |
| PC-42059 |
TA-02
p38 MAPK inhibitor
|
TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM. |
| PC-42512 |
SB 202190
p38 MAPK inhibitor
|
SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively. |
| PC-42526 |
VX-745
p38α MAPK inhibitor
|
Neflamapimod (VX-745) is a potent and selective p38α kinase inhibitor with IC50 of 9 nM. |
| PC-42520 |
Doramapimod
p38 MAPK inhibitor
|
Doramapimod (BIRB-796) is a highly potent p38 MAPK inhibitor with Kd of 0.1 nM. |
