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Chemical Structure : MW-150
CAS No.: 1628502-91-9
Catalog No.: PC-60434Not For Human Use, Lab Use Only.
MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $178 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
MW-150 effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models.
MW-150 also can selectively modulate neuroinflammatory responses associated with pathology progression.
| M.Wt | 381.483 | |
| Formula | C24H23N5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine |
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1. Roy SM, et al. ACS Chem Neurosci. 2015 Apr 15;6(4):666-80.
2. Zhou Z, et al. J Neuroinflammation. 2017 Apr 5;14(1):75.
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