Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-p38 MAPK-MW-150
MW-150

Chemical Structure : MW-150

CAS No.: 1628502-91-9

MW-150 (MW01-18-150SRM;MW 150;MW150)

Catalog No.: PC-60434Not For Human Use, Lab Use Only.

MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.

Packing Price Stock Quantity
5 mg $118 In stock
10 mg $178 In stock
25 mg $298 In stock
50 mg $488 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
MW-150 effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models.
MW-150 also can selectively modulate neuroinflammatory responses associated with pathology progression.

Physicochemical Properties

M.Wt 381.483
Formula C24H23N5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine

References

1. Roy SM, et al. ACS Chem Neurosci. 2015 Apr 15;6(4):666-80.

2. Zhou Z, et al. J Neuroinflammation. 2017 Apr 5;14(1):75.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: