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Cat. No. Product Name CAS No. Information
PC-38808

CCT369260

2253878-44-1 CCT369260 is a highly potent, orally active BCL6 degrader with DC50 of 54 nM in cellular BCL6 degradation assays.
PC-72240

BAX inhibitor BAI1

335165-68-9 BAX inhibitor BAI1 (BAI1) is a small-molecule allosteric inhibitor of BAX, bind directly to BAX and inhibits tBID-induced BAX-mediated membrane permeabilization with IC50 of 3.4 uM.
PC-38265

EU-5346

315698-17-0 EU-5346 (ML311) is a small molecule Mcl-1 inhibitor with IC50 of 0.31 uM, potently and selectively disrupts Mcl-1/Bim interaction.
PC-35691

MIK665

1799631-75-6 MIK665 (S-64315, MIK-665) is a novel potent, selective Mcl-1 inhibitor (IC50=1.8 nM) with potential pro-apoptotic and antineoplastic activities.
PC-63502

S55746

1448584-12-0 S55746 (BCL201, Servier-1) is a novel potent, selective, orally bioavailable inhibitor of BCL-2 with Ki of 1.3 nM, 70- 400 fold selectivity over BCL-XL, on significant binding to MCL-1 and BFL-1.
PC-62551

Mcl-1-Puma inhibitor 8

678158-55-9 Mcl-1-Puma inhibitor 8 is a small-molecule dual-acting compound that targets the apoptotic Mcl-1-PUMA interface with Ki of 0.3 uM (Mcl-1, FPA), reduces multiple cancer cells and inhibits PUMA-mediated apoptosis.
PC-62538

BCL6-IN-8

2204272-40-0 BCL6-IN-8 (BCL6-i) is a potent, irreversible and cell-active BCL6 inhibitor with inact/KI value of 1.9 × 104 M-1 s-1, targets Cys53 located at the protein-protein interaction interface.

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