| Cat. No. |
Product Name |
Information |
| PC-21117 |
PDCD2 ligand 7e
PDCD2 modulator
|
PDCD2 ligand 7e is a small molecule that may directly bind to PDCD2, rescues PDCD2 degradation induced by PDCD2 degrader 10e. |
| PC-21059 |
WK499
BCL-6 inhibitor
|
WK499 (WK-499) is a small molecule inhibitor of BCL6 with IC50 of 11.7 nM in HTRF assay, directly binds to BCL6 BTB (SPR KD=148 nM), inhibits the BCL6-mediated transcriptional repression activity. |
| PC-20626 |
CCT373567
BCL6 inhibitor
|
CCT373567 is a potent, selective and cell-active BCL6 inhibitor with IC50 of 2.9 nM in TR-FRET assays, and 25.9 nM in NanoBRET cellular inhibition assays. |
| PC-49189 |
DC-B01
BCL2 BH4 inhibitor
|
DC-B01 is a novel small molecule BCL-2 inhibitor that binds to the BH4 domain with KD of 2.16 uM, disrupts the BCL-2/c-Myc interaction and consequently suppresses the transcriptional activity of c-Myc. |
