Bcl-2 compound (inhibitors, antagonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21258	M109S Bax inhibitor	M109S is a small molecule protecting cells from mitochondria-dependent apoptosis wtih EC50 of 23.4 nM in iBax cells, directly interacts with Bax (Kd=153 nM, MST assay) and inhibits Bax activation.
PC-21117	PDCD2 ligand 7e PDCD2 modulator	PDCD2 ligand 7e is a small molecule that may directly bind to PDCD2, rescues PDCD2 degradation induced by PDCD2 degrader 10e.
PC-21059	WK499 BCL-6 inhibitor	WK499 (WK-499) is a small molecule inhibitor of BCL6 with IC50 of 11.7 nM in HTRF assay, directly binds to BCL6 BTB (SPR KD=148 nM), inhibits the BCL6-mediated transcriptional repression activity.
PC-20626	CCT373567 BCL6 inhibitor	CCT373567 is a potent, selective and cell-active BCL6 inhibitor with IC50 of 2.9 nM in TR-FRET assays, and 25.9 nM in NanoBRET cellular inhibition assays.
PC-49189	DC-B01 BCL2 BH4 inhibitor	DC-B01 is a novel small molecule BCL-2 inhibitor that binds to the BH4 domain with KD of 2.16 uM, disrupts the BCL-2/c-Myc interaction and consequently suppresses the transcriptional activity of c-Myc.

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