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Lacutoclax

Chemical Structure : Lacutoclax

CAS No.: 2291166-56-6

Lacutoclax (LP-108, LP108)

Catalog No.: PC-23094Not For Human Use, Lab Use Only.

Lacutoclax (LP-108) is a highly potent and selective inhibitor of BCL-2 with comparable or more potent in vitro inhibitory activity compared to venetoclax.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Lacutoclax (LP-108) is a highly potent and selective inhibitor of BCL-2 with comparable or more potent in vitro inhibitory activity compared to venetoclax.

Physicochemical Properties

M.Wt 923.53
Formula C48H55ClN8O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-2-[(3R)-2,3-dihydro-3-methylpyrrolo[3′,2′:5,6]pyrido[2,3-b][1,4]oxazin-1(6H)-yl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]benzamide

References

1. Patent WO2021066873 A1 2021-04-08.

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