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Request The Product List ofCyclin-dependent Kinase (CDK) Cyclin-dependent Kinase (CDK)

Cat. No. Product Name CAS No. Information
PC-47100

YPN-005

YPN-005 (YPN005) is a highly potent, selective inhibitor of cyclin-dependent kinase 7 (CDK7) with IC50 of 31 nM, with low inhibition for CDK2 and CDK5.
PC-72755

AS-0141

1402057-88-8 Monzosertib (AS 0141) is a potent, selective, orally bioavailable CDC7 inhibitor with IC50 of 2.4 nM.
PC-38299

(R)-CR8

294646-77-8 (R)-CR8 is a potent CDK1/2/5/7/9 inhibitor, inhibits CDK1/cyclin B (IC50, 90 nM), CDK2/cyclin A (72 nM), CDK2/cyclin E (41 nM), CDK5/p25 ( 110 nM), CDK7/cyclin H (1.1 uM), CDK9/cyclin T (0.18 uM) and CK1δ/ε (0.4 uM).
PC-38278

KB-0742

2416873-83-9 KB-0742 (KB0742) is a potent, orally bioavailable, selective CDK9 inhibitor with IC50 of 6 nM (CDK9/cyclin T1 inhibition).
PC-36163

FMF-04-159-2

2364489-81-4 FMF-04-159-2 is a potent, selective, covalent CDK14 inhibitor (IC50=86 nM) with pan-TAIRE family specificity (CDKs 14-18).
PC-36145

YKL-5-124

1957203-01-8 YKL-5-124 is a novel potent, selective, and covalent CDK7 inhibitor (IC50=53.5 nM), inhibits CDK7/CycH/MAT1 enzymatic activity with IC50 of 9.7 nM.
PC-35969

PF-06873600

2185857-97-8 PF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.

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