| Cat. No. |
Product Name |
Information |
| PC-21051 |
SW394703
|
SW394703 is a novel DDB1-dependent molecular glue degrader for cyclin K, SW394703 is toxic to HCT116 cells (IC50=1.2 uM). |
| PC-49789 |
RGB-286147
|
RGB-286147 (RGB 286147) is a proteome-wide CDK/CRK-specific kinase inhibitor with IC50 of 48 and 15 nM for CDK1/CycB and CDK2/CycE, respectively. |
| PC-49485 |
KB-0742 dihydrochloride
|
KB-0742 (KB0742) is a potent, orally bioavailable, selective CDK9 inhibitor with IC50 of 6 nM (CDK9/cyclin T1 inhibition). |
| PC-49260 |
ZSQ836
|
ZSQ836 (ZSQ 836) is a potent, selective and orally bioavailable CDK12/CDK13 covalent inhibitor with IC50 of 32 nM (CDK12), covalently interacts with Cys1039 of CDK12. |
| PC-49204 |
SNX631
|
SNX631 (SNX-631) is a potent, selective inhibitor of CDK8/19 Mediator kinase with IC50 of 10.3 nM in the NF κB-dependent cell-based assays. |
| PC-49131 |
Culmerciclib
|
Culmerciclib is a potent, selective CDK4/6 inhibitor with potential for treating cancers such as breast cancer and lung cancer. |
| PC-49130 |
Crozbaciclib
|
Crozbaciclib is a highly potent, selective, blood-brain barrier (BBB) permeable CDK4/6 inhibitor with IC50 values of 3 nM and 1 nM against CDK4/cyclin D1 and CDK6/cyclin D3, respectively. |
