| Cat. No. |
Product Name |
Information |
| PC-23694 |
P162-0948
CDK8 inhibitor
|
P162-0948 is a potent, selective cyclin-dependent kinase 8 (CDK8) inhibitor with IC50 of 50.4 nM, disrupts TGF-β1-induced cell migration. |
| PC-23612 |
KY-065
CDK8 inhibitor
|
KY-065 is a potent, selective and ATP-competitive CDK8/19 inhibitor with IC50 of 4.4/3.6 nM respectively, without affecting the activities of other CDK family members. |
| PC-23502 |
BSJ-01-175
CDK12/13 inhibitor
|
BSJ-01-175 is a potent, selective dual CDK12/13 covalent inhibitor with IC50 of 156 nM (CDK12/CycK) and 282.6 nM（CDK3/CycK), targets cysteine Cys1039 on CDK12 (or Cys1017 on CDK13). |
| PC-23151 |
CDK-TCIP2
|
CDK-TCIP2 is a bivalent molecule linking CDK9 inhibitor SNS-032 to BCL6 ligand BI3812, activates BCL6-regulated transcription, potently and specifically kills BCL6-overexpressing cells with EC50 of 0.9 nM for SUDHL5 cells. |
| PC-23150 |
CDK-TCIP1
3008612-35-6
|
CDK-TCIP1 is a bivalent molecule linking CDK9 inhibitor SNS-032 to BCL6 ligand BI3812, potently and specifically kills BCL6-overexpressing cells with EC50 of 7.7 nM for SUDHL5 cells. |
| PC-23060 |
Tacaciclib
CDK7 inhibitor
|
Tacaciclib (XL102, AUR102) is a potent, orally bioavailable, highly selective covalent CDK7 inhibitor. |
| PC-23058 |
BPI-16350
CDK4/6 inhibitor
|
BPI-16350 (Tibremciclib) is a highly potent, selective CDK4/6 inhibitor with IC50 of 2.21 nM and 0.4 nM for CDK4/cyclinD1 and CDK6/cyclinD1, with less inhibition of CDK9 (IC50=91.6 nM). |
| PC-23046 |
Myrtleciclib
CDK4/6/9 inhibitor
|
Myrtleciclib (VS2 370) is a potent, selective CDK4/6/9 inhibitor. |
| PC-23020 |
YK-2168 hydrochloride
CDK9 inhibitor
|
YK-2168 hydrochloride is a potent, selective CDK9 inhibitor with IC50 of 5.9 nM, 45- and 72-fold selective over CDK1 and CDK2. |
| PC-23019 |
YK-2168
CDK9 inhibitor
|
YK-2168 is a potent, selective CDK9 inhibitor with IC50 of 5.9 nM, 45- and 72-fold selective over CDK1 and CDK2. |
| PC-22927 |
TMX-2039
CDK inhibitor
|
TMX-2039 is a potent, multi-CDK inhibitor with low nanomolar enzymatic IC50s for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9). |
| PC-22926 |
TMX-3013
CDK inhibitor
|
TMX-3013 is a potent, multi-CDK inhibitor with IC50 of 0.9/<0.5/0.5/24.5/15.6 nM for CDK1/2/5/4/6 respectively. |
