| Cat. No. |
Product Name |
Information |
| PC-22926 |
TMX-3013
CDK inhibitor
|
TMX-3013 is a potent, multi-CDK inhibitor with IC50 of 0.9/<0.5/0.5/24.5/15.6 nM for CDK1/2/5/4/6 respectively. |
| PC-22841 |
CDKL3 inhibitor HZ1
CDKL3 inhibitor
|
CDKL3 inhibitor HZ1 (C3I-22) is a first-in-class, specific inhibitor of CDKL3 (Cyclin-dependent kinase like 3) inhibitor with Kd of 5.16 uM, blocks CDKL3 mediated cell cycle progression both in vitro and in vivo |
| PC-22396 |
CDKL2 inhibitor 9
CDKL2 inhibitor
|
CDKL2 inhibitor 9 is a selective cyclin-dependent kinase-like 2 (CDKL2, KKIAMRE, P56) chemical probe inhibitor with enzyme IC50 of 230 nM in radiometric enzymatic assays. |
| PC-22118 |
AZD8421
CDK2 inhibitor
|
AZD8421 (AZD-8421) is a potent, highly selective CDK2 inhibitor with IC50 of 9 nM, >300-fold selectivity over CDK9. |
| PC-22032 |
KY-273
CDK8/19 inhibitor
|
KY-273 (KY273) is a potent, specific CDK8/19 inhibitor with IC50 of 29.1 and 44.7 nM respectively, promotes osteoblast differentiation and has cortical-bone-selective osteogenic effects. |
| PC-21964 |
dCeMM4
Cyclin K degrader
|
dCeMM4 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex. |
| PC-21963 |
dCeMM3
Cyclin K degrader
|
dCeMM3 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex. |
| PC-21962 |
dCeMM2
Cyclin K degrader
|
dCeMM2 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex. |
| PC-21922 |
LDC3140
CDK7 inhibitor
|
LDC3140 is a potent, selective CDK7 inhibitor with IC50 of <5 nM, >500-fold selective over CDK1/2/4/6/9. |
| PC-21886 |
CVT-313
CDK2 inhibitor
|
CVT-313 (CVT313) is a potent, specific CDK2 inhibitor with IC50 of 0.5 uM (CDK2/cyclin A), equally inhibits CDK2/cyclin E. |
| PC-21703 |
CP681301
CDK5 inhibitor
|
CP681301 is a potent, highly specific CDK5 inhibitor, completely inhibits both CDK5-P35 and CDK5-P25 at 1 uM. |
| PC-21681 |
XPW1
CDK9 inhibitor
|
XPW1 is a potent and selective CDK9 inhibitor with excellent anti-ccRCC activity and low toxicity. |
