| Cat. No. |
Product Name |
Information |
| PC-60480 |
Fascaplysin chloride
|
A potent CDK4/cyclin D1 with IC50 of 0.35 uM, 10-fold less potent for significantly for CDK6/cyclin D1 and does not inhibit other Cdks and tyrosine kinases. |
| PC-60396 |
Trilaciclib hydrochloride
|
A novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 4 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively. |
| PC-42067 |
R-547
|
A potent, selective and ATP-competitive CDK inhibitor with Ki of 1/3/1 nM for CDK1/2/4, respectively. |
| PC-45446 |
Purvalanol B
|
A potent, cell-permeable, selective inhibitor of CDK with IC50s of 6, 6, 9, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5-p35 respectively. |
| PC-45447 |
Purvalanol A
|
A potent, cell-permeable, selective inhibitor of CDK with IC50s of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. |
| PC-42050 |
Flavopiridol hydrochloride
|
A potent, ATP-competetive CDKs inhibitor with IC50 of 30, 170, 100 nM for CDk1, 2, 4, respectively. |
| PC-42049 |
Flavopiridol
|
A potent, ATP-competetive CDKs inhibitor with IC50 of 30, 170, 100 nM for CDk1, 2, 4, respectively. |
| PC-42777 |
PHA-793887
|
A potent inhibitor of CDK2/5/7 with IC50 of 8/5/10 nM respectively. |
| PC-45863 |
Palbociclib hydrochloride
|
A potent and selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. |
| PC-45862 |
Palbociclib
|
A potent and selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. |
| PC-45792 |
Roscovitine
|
A potent and selective CDK inhibitor with IC50 of 0.2 uM, 0.65 uM, and 0.7 uM for CDK5, Cdc2, and CDK2, respectively. |
| PC-42259 |
NSC23005 sodium
|
A novel specific, effective p18 (p18INK4C) inhibitor that can selectively promote HSCs expansion with EC50 of 5.21 nM. |
