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Cat. No. Product Name Information
PC-60398

G1T38 dihydrochloride

CDK4/6 inhibitor

Lerociclib (G1T38) dihydrochloride is a potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.
PC-60397

G1T38

CDK4/6 inhibitor

G1T38 (Lerociclib, G1T 38) is a novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.
PC-60395

Trilaciclib

CDK4/6 inhibitor

Trilaciclib (G1T28) is a novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 4 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.
PC-60329

NVP-2

CDK9 inhibitor

NVP-2 is a potent, selective, ATP-competitive CDK9 inhibitor with IC50 of <0.514 nM (CDK9/CyclinT).
PC-70170

GW-8510

CDK2 inhibitor

GW-8510 (GW8510) is a potent, selective inhibitor of CDK2 with IC50 of 10 nM.
PC-70116

NU-6027

CDK1/2 inhibitor

NU-6027 (NU6027) is an ATP-competitive inhibitor of CDK1 and CDK2 with Ki of 2.5 uM and 1.3 uM respectively.
PC-60298

MSC2530818

CDK8 inhibitor

MSC-2530818 (MSC 2530818, MSC2530818) is a potent, selective, and orally bioavailable CDK8 inhibitor with IC50 of 2.6 nM.
PC-45559

NU-6300

CDK2 inhibitor

NU-6300 is the first covalent, irreversible, ATP-Competitive CDK2 inhibitor with Ki of 6 nM.
PC-44628

Senexin-A

CDK8/CDK19 inhibitor

Senexin-A is a selective inhibitor of CDK8 (IC50=0.28 uM) and CDK19, inhibits CDK8 and CDK19 ATP site binding with Kd50 of 0.83 uM and 0.31 uM, respectively.
PC-45491

SU-9516

CDK2 inhibitor

SU-9516 is a potent, selective CDK2 inhibitor with IC50 of 22 nM.
PC-46009

THZ1 hydrochloride

CDK7 inhibitor

THZ1 hydrochloride is a potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM.
PC-46008

THZ1

CDK7 inhibitor

THZ1 is a potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM, also weakly inhibits CDK12 with IC50 of 250 nM.

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