| Cat. No. |
Product Name |
Information |
| PC-49485 |
KB-0742 dihydrochloride
|
KB-0742 (KB0742) is a potent, orally bioavailable, selective CDK9 inhibitor with IC50 of 6 nM (CDK9/cyclin T1 inhibition). |
| PC-49260 |
ZSQ836
|
ZSQ836 (ZSQ 836) is a potent, selective and orally bioavailable CDK12/CDK13 covalent inhibitor with IC50 of 32 nM (CDK12), covalently interacts with Cys1039 of CDK12. |
| PC-49204 |
SNX631
|
SNX631 (SNX-631) is a potent, selective inhibitor of CDK8/19 Mediator kinase with IC50 of 10.3 nM in the NF κB-dependent cell-based assays. |
| PC-49131 |
Culmerciclib
|
Culmerciclib is a potent, selective CDK4/6 inhibitor with potential for treating cancers such as breast cancer and lung cancer. |
| PC-49130 |
Crozbaciclib
|
Crozbaciclib is a highly potent, selective, blood-brain barrier (BBB) permeable CDK4/6 inhibitor with IC50 values of 3 nM and 1 nM against CDK4/cyclin D1 and CDK6/cyclin D3, respectively. |
| PC-49076 |
CDK inhibitor 24
|
CDK inhibitor 24 is a potent inhibitor of cyclin-dependent kinases (CDKs) with IC50 of 4/20/64 nM for CDK2/9/12, respectively. |
| PC-47100 |
YPN-005
|
YPN-005 (YPN005) is a highly potent, selective inhibitor of cyclin-dependent kinase 7 (CDK7) with IC50 of 31 nM, with low inhibition for CDK2 and CDK5. |
