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Request The Product List ofCyclin-dependent Kinase (CDK) Cyclin-dependent Kinase (CDK)

Cat. No. Product Name Information
PC-21922

LDC3140

CDK7 inhibitor

LDC3140 is a potent, selective CDK7 inhibitor with IC50 of <5 nM, >500-fold selective over CDK1/2/4/6/9.
PC-21886

CVT-313

CDK2 inhibitor

CVT-313 (CVT313) is a potent, specific CDK2 inhibitor with IC50 of 0.5 uM (CDK2/cyclin A), equally inhibits CDK2/cyclin E.
PC-21703

CP681301

CDK5 inhibitor

CP681301 is a potent, highly specific CDK5 inhibitor, completely inhibits both CDK5-P35 and CDK5-P25 at 1 uM.
PC-21681

XPW1

CDK9 inhibitor

XPW1 is a potent and selective CDK9 inhibitor with excellent anti-ccRCC activity and low toxicity.
PC-21562

GFH009

CDK9 inhibitor

GFH009 is a potent, selective CDK9 inhibitor, inhibits the activity of the CDK9/cyclin T1 regulatory complex of P-TEFb.
PC-21527

TMX-2039

pan CDK inhibitor

TMX-2039 is a pan-CDK inhibitor with low nanomolar enzymatic IC50s (0.5-50 nM) for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9).
PC-21500

INX-315

CDK2 inhibitor

INX-315 (INX315) is a highly potent, selective CDK2 inhibitor with IC50 of 0.6 and 2.5 nM for CDK2/cyclin E1 and CDK2/cyclin A2 respectively, shows high selectivity over other CDK family members.
PC-21462

CDDD11-8

CDK9/FLT3-ITD inhibitor

CDDD11-8 is a potent, selective, orally bioavailable CDK9 inhibitor with Ki of 8 nM, shows >50-fold selectivity over other CDKs, also inhibits FLT3-ITD with Ki of 13 nM.
PC-21140

Cyclin K degrader DS17

cyclin K degarder

Cyclin K degrader DS17 is a selective cyclin K molecular glue degrader with TR-FRET EC50 of 19 nM.
PC-21090

RGB-286199

CDK inhibitor

RGB-286199 (GPC-286199) is a potent broad spectrum CDKs (cyclin dependent kinases) inhibitor with IC50 of 5-100 nM against CDKs 1-6, shows antiproliferative activity in vitro and in vivo.
PC-21089

RGB-286638

CDK inhibitor

RGB-286638 is a small-molecule multi-targeted cyclin-dependent kinase (CDK) inhibitor with IC50 of 1-5 nM for cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5.
PC-21088

LDC000067

CDK9 inhibitor

LDC000067 (LDC067) is a highly specific inhibitor of CDK9 with IC50 of 44 nM (CDK9-Cyclin T1), highly selective over other CDKs in the range of 55-fold (CDK2) to over 230-fold (CDK6 and CDK7).

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