| Cat. No. |
Product Name |
Information |
| PC-72467 |
LY3405105
CDK7 inhibitor
|
LY3405105 (LY-3405105) is a potent, selective, orally active CDK7 inhibitor with an IC50 of 92.8 nM, shows potential antineoplastic activity. |
| PC-38063 |
bio-THZ1
|
bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7.. |
| PC-35525 |
CDK12 inhibitor 2
|
CDK12 inhibitor 2 is a potent, selective, non-covalent CDK12 inhibitor with IC50 of 52 nM, displays >192-fold selectivity over CDK2/7/8/9. |
| PC-35248 |
Cdc7 inhibitor
|
Cdc7 inhibitor is a potent inhibitor of Cdc7 kinase with pIC50 of 10.01 against CDC7/DBF4 in TR-FRET assays.. |
| PC-43411 |
CDK9-IN-1
|
CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.. |
| PC-43342 |
CDK9-IN-2
|
CDK9-IN-2 is a potent and selective CDK9 inhibitor with IC50 of <8 nM, example 4 in patent WO2011026917A1.. |
| PC-62848 |
CDK9-IN-4d
|
CDK9-IN-1 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition. |
| PC-62821 |
CGP-74514A hydrochloride
|
CGP-74514A hydrochloride is a potent CDK1 inhibitor with IC50 of 25 nM. |
| PC-61136 |
CDK2 inhibitor 73
|
A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).. |
| PC-61020 |
Cdc7 inhibitor 7c
|
A highly potent, selective and time-dependent Cdc7 kinase inhibitor with IC50 of 0.7 nM with slow dissociation property, with 200-fold and >14,000-fold selectivity over CDK2 and ROCK1, respectively. |
| PC-60492 |
CDK12 inhibitor E9 racemate
|
A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux. |
| PC-60491 |
CDK12 inhibitor E9 R-isomer
|
A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux. |
