| Cat. No. |
Product Name |
Information |
| PC-42036 |
LY3177833
CDC7 inhibitor
|
LY3177833 is a potent and selective CDC7 inhibitor with IC50 of 3.3 nM. |
| PC-42060 |
AZD-5438
CDK1/2/9 inhibitor
|
AZD-5438 (AZD5438) potent and oral inhibitor of CDK1/2/9 with IC50 of 16/6/20 nM, respectively. |
| PC-42425 |
Senexin B
CDK8/CDK19 inhibitor
|
Senexin B (SNX2-1-165) is a highly potent, selective and orally available CDK8/CDK19 inhibitor with IC50 of 24-50 nM. |
| PC-42527 |
JNJ-7706621
CDK/Aurora inhibitor
|
JNJ-7706621 is a potent, dual CDK/Aurora kinase inhibitor with IC50 of 9/4/11/15 nM for CDK1/CDK2/Aurora A/Aurora B respectively. |
| PC-23151 |
CDK-TCIP2
|
CDK-TCIP2 is a bivalent molecule linking CDK9 inhibitor SNS-032 to BCL6 ligand BI3812, activates BCL6-regulated transcription, potently and specifically kills BCL6-overexpressing cells with EC50 of 0.9 nM for SUDHL5 cells. |
| PC-23150 |
CDK-TCIP1
3008612-35-6
|
CDK-TCIP1 is a bivalent molecule linking CDK9 inhibitor SNS-032 to BCL6 ligand BI3812, potently and specifically kills BCL6-overexpressing cells with EC50 of 7.7 nM for SUDHL5 cells. |
| PC-23060 |
Tacaciclib
CDK7 inhibitor
|
Tacaciclib (XL102, AUR102) is a potent, orally bioavailable, highly selective covalent CDK7 inhibitor. |
| PC-23058 |
BPI-16350
CDK4/6 inhibitor
|
BPI-16350 (Tibremciclib) is a highly potent, selective CDK4/6 inhibitor with IC50 of 2.21 nM and 0.4 nM for CDK4/cyclinD1 and CDK6/cyclinD1, with less inhibition of CDK9 (IC50=91.6 nM). |
| PC-23046 |
Myrtleciclib
CDK4/6/9 inhibitor
|
Myrtleciclib (VS2 370) is a potent, selective CDK4/6/9 inhibitor. |
| PC-23020 |
YK-2168 hydrochloride
CDK9 inhibitor
|
YK-2168 hydrochloride is a potent, selective CDK9 inhibitor with IC50 of 5.9 nM, 45- and 72-fold selective over CDK1 and CDK2. |
| PC-23019 |
YK-2168
CDK9 inhibitor
|
YK-2168 is a potent, selective CDK9 inhibitor with IC50 of 5.9 nM, 45- and 72-fold selective over CDK1 and CDK2. |
| PC-22927 |
TMX-2039
CDK inhibitor
|
TMX-2039 is a potent, multi-CDK inhibitor with low nanomolar enzymatic IC50s for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9). |
