Chemical Structure : PHA-793887
CAS No.:
718630-59-2
PHA-793887
(PHA793887)
Catalog No. : PC-42777Not For Human Use, Lab Use Only.
PHA-793887 is a potent inhibitor of CDK2/5/7 with IC50 of 8/5/10 nM respectively, >6-fold less potency on CDK1/4/6.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $118 In stock 0 1 2 3 4 5 25 mg $218 In stock 0 1 2 3 4 5 50 mg $358 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4277701
Biological Activity
PHA-793887 is a potent inhibitor of CDK2/5/7 with IC50 of 8/5/10 nM respectively, >6-fold less potency on CDK1/4/6.
Physicochemical Properties
M.Wt
361.4818
Formula
C19H31N5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-
References
1. Brasca MG, et al. Bioorg Med Chem.
2. Locatelli G, et al. Mol Cancer Ther.
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