| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38692 |
FT709
|
2413991-74-7 |
FT709 is a potent, highly selective USP9X inhibitor with IC50 of 82 nM in biochemical assays, reduces CEP55 expression in BxPC3 pancreatic cancer cells with IC50 of 131 nM. |
| PC-72835 |
EN523
|
2094893-05-5 |
EN523 (EN-523) is a small molecule covalent ligand that targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1, OTUB1 recruiter component of DUBTAC NJH-2-057. |
| PC-72253 |
FT385
|
|
FT385 (FT3967385) is a potent, selective USP30 inhibitor with biochemical IC50 of 1.5 nM. |
| PC-72252 |
USP30 inhibitor Compound 39
|
2242582-40-5 |
USP30 inhibitor Compound 39 (CMPD-39) is a highly selective inhibitor of USP30 with IC50 of 20 nM in an in vitro assay of enzyme activity, >100-fold selectivity over other DUBs. |
| PC-38072 |
XL177A
|
2417089-74-6 |
XL177A is a potent, selective, irreversible USP7 inhibitor with IC50 of 0.34 nM.
XL177A inhibits HA-Ub-VS labeling with IC50s of 85 and 8 nM following 30min and 4hr compound preincubations, respectively. |
| PC-36022 |
KL001
|
309928-48-1 |
KL001 (KL-001) is a small molecule that specifically interacts with cryptochrome (CRY) and small molecule modulator of the circadian clock. |
| PC-35682 |
IU1-248
|
2307472-03-1 |
IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1. |
