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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name CAS No. Information
PC-38692

FT709

2413991-74-7 FT709 is a potent, highly selective USP9X inhibitor with IC50 of 82 nM in biochemical assays, reduces CEP55 expression in BxPC3 pancreatic cancer cells with IC50 of 131 nM.
PC-72835

EN523

2094893-05-5 EN523 (EN-523) is a small molecule covalent ligand that targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1, OTUB1 recruiter component of DUBTAC NJH-2-057.
PC-72253

FT385

FT385 (FT3967385) is a potent, selective USP30 inhibitor with biochemical IC50 of 1.5 nM.
PC-72252

USP30 inhibitor Compound 39

2242582-40-5 USP30 inhibitor Compound 39 (CMPD-39) is a highly selective inhibitor of USP30 with IC50 of 20 nM in an in vitro assay of enzyme activity, >100-fold selectivity over other DUBs.
PC-38072

XL177A

2417089-74-6 XL177A is a potent, selective, irreversible USP7 inhibitor with IC50 of 0.34 nM. XL177A inhibits HA-Ub-VS labeling with IC50s of 85 and 8 nM following 30min and 4hr compound preincubations, respectively.
PC-36022

KL001

309928-48-1 KL001 (KL-001) is a small molecule that specifically interacts with cryptochrome (CRY) and small molecule modulator of the circadian clock.
PC-35682

IU1-248

2307472-03-1 IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1.

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