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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name Information
PC-20186

USP14 inhibitor 1

USP14 inhibitor

USP14-IN-1 is a specific small molecule USP14 inhibitor with IC50 of 0.5 uM.
PC-20185

IU2-6

USP14 inhibitor

IU2-6 is a small molecule USP14 inhibitor, shows 74% inhibition at 8 uM.
PC-20184

GSK2643943A

USP20 inhibitor

GSK2643943A is a specific, cell penetrant small molecule inhibitor of deubiquitinating enzyme USP20 with IC50 of 160 nM (USP20/Ub-Rho).
PC-20004

TG2-179-1

BAP1 inhibitor

TG2-179-1 is a potent, selective and covalently inhibitor of deubiquitinase (DUB) BRCA1-associated protein-1 (BAP1), covalently binds to the active site of BAP1 (Cys91), exhibits potent cytotoxic activity against colon cancer cells.
PC-20001

CAS-12290-201

VCPIP1 inhibitor

CAS-12290-201 is a potent and selective inhibitor of deubiquitinating enzyme (DUB) VCPIP1 with IC50 of 70 nM, covalently and specificly targets the catalytic cysteine of VCPIP1 with little to no activity toward other cellular DUBs.
PC-49863

BAY-728

BAY-805 negative control

BAY-728 (BAY728, (S)-BAY-805) is a less potent enantiomer and negative control compound of BAY-805, which is a potent and selective Inhibitor of USP21.
PC-49862

BAY-805

USP21 inhibitor

BAY-805 (BAY805) is the first highly potent, selective and non-covalent USP21 inhibitor with IC50 of 6 nM and 2 nM in HTRF and Ub-rhodamine biochemical assays (hUSP21), respectively.
PC-49744

BML-260

JSP-1 (DUSP22) inhibitor

BML-260 (BML260) is a potent inhibitor of dual-specific phosphatase JSP-1 (JNK Stimulatory Phosphatase-1, DUSP22) and stimulator of uncoupling protein 1 (UCP-1) expression in adipocytes.
PC-49689

I-138

UPS1 inhibitor

I-138 (I 138) is a potent, specific small molecule USP1-UAF1 inhibitor with IC50 of 4.1 nM, binds to USP1-UAF1 at an allosteric pocket synergistically with ubiquitin.
PC-49626

8RK64

UCHL1 inhibitor

8RK64 is a covalent small molecule inhibitor of ubiquitin carboxy-terminal hydrolase L1 (UCHL1, PGP9.5, PARK5) enzyme with IC50 of 0.32 uM, >80-fold selectivity over UCHL3 and UCHL5.
PC-49546

Usp22i-S02

USP22 inhibitor

Usp22i-S02 (Usp22 inhibitor S02) is a specific small-molecule inhibitor of the Foxp3-specific deubiquitinase USP22, down-regulates Foxp3 expression in Treg cells in a Usp22- but not Usp21-dependent manner.
PC-49371

GK13S

UCHL1 inhibitor

GK13S is a highly potent, specific and covalent inhibitor of deubiquitinase UCHL1 with IC50 of 87 nM, displays exquisite specificity for UCHL1 over the other UCH family members (IC50>10 uM).

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