| Cat. No. |
Product Name |
Information |
| PC-61234 |
IU-1
USP14 inhibitor
|
IU-1 (USP14 inhibitor IU1) is a specific, small molecule inhibitor of deubiquitinating enzyme USP14 with IC50 of 4-5 uM. |
| PC-60494 |
XL188
USP7 inhibitor
|
XL188 (XL-188) is a potent, selective, non-covalent active-site inhibitor of USP7 with IC50 of 90 nM and 193 nM for USP7 full length enzyme and catalytic domain, respectively. |
| PC-60089 |
GNE-6776
USP7 inhibitor
|
GNE-6776 is a novel potent, specific, non-covalent, orally bioavailable USP7 inhibitor with IC50 of 1.34 uM. |
| PC-60088 |
FT-671
USP7 inhibitor
|
FT-671 is a novel potent, specific, non-covalent USP7 inhibitor with Kd of 65 nM (USP7 catalytic domain). |
| PC-60087 |
FT-827
USP7 inhibitor
|
FT-827 is a novel potent, specific, covalent USP7 inhibitor with Kd of 7.8 uM (USP7 catalytic domain). |
| PC-60026 |
USP25 and 28 inhibitor AZ2
USP25/USP28 inhibitor
|
USP25 and 28 inhibitor AZ2 is a potent, selective, dual USP25/28 inhibitor with IC50 of 0.9/0.9 uM, respectively. |
| PC-60023 |
USP25 and 28 inhibitor AZ1
USP25/USP28 inhibitor
|
USP25 and 28 inhibitor AZ1 (AZ1) is a potent, selective, dual USP25/28 inhibitor with IC50 of 0.7/0.6 uM, respectively. |
| PC-60012 |
GNE-6640
USP7 inhibitor
|
GNE-6640 (GNE6640) is a potent, selective and non-covalent USP7 inhibitor with IC50 of 0.75 uM. |
| PC-60003 |
USP7 inhibitor ALM4
USP7 inhibitor
|
USP7 inhibitor ALM4 (AD-04) is a highly potent, selective, allosteric USP7 inhibitor with IC50 of 6 nM in FP assays, SPR Kd of 2 nM. |
| PC-42241 |
Ubiquitin Isopeptidase-IN-G5
USP5 inhibitor
|
Ubiquitin Isopeptidase-IN-G5 (NSC 144303) is a small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases. |
| PC-42231 |
NSC632839
DUBs inhibitor
|
NSC632839 is a small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases, inhibits USP2, USP7, and SENP2 with EC50 values of 45 μM, 37 μM, and 9.8 μM, respectively. |
| PC-45498 |
LDN-57444
UCHL1 inhibitor
|
LDN57444 is a potent, reversible, competitive, active site-directed UCHL1 inhibitor with IC50 of 0.88 uM. |
