USP7i-1 |CAS:1381291-36-6 Probechem Biochemicals

Chemical Structure : USP7i-1

CAS No.: 1381291-36-6

Catalog No.: PC-61935Not For Human Use, Lab Use Only.

USP7i-1 (USP7-IN-1) is a potent, selective USP7 inhibitor with IC50 of 77 uM.

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10 mg	$398	In stock
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Biological Activity

USP7i-1 (USP7-IN-1) is a potent, selective USP7 inhibitor with IC50 of 77 uM.

USP7i-1 shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3.

USP7i-1 inhibits the proliferation of HCT116 cells with GI50 of 67 uM.

M.Wt	425.913
Formula	C23H24ClN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one

1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.

2. Kessler BM. Expert Opin Ther Pat. 2014 May;24(5):597-602.