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Request The Product List ofHCV HCV

Cat. No. Product Name Information
PC-20275

Nesbuvir

HCV NS5B inhibitor

Nesbuvir (HCV-796) is a selective, non-nucleoside HCV nonstructural protein 5B (NS5B) polymerase inhibitor with IC50 of 0.01-0.14 uM for genotype 1, EC50 of 5 nM and 9 nM against genotype 1a and 1b replicon.
PC-73081

Amphihevir

HCV NS4B inhibitor

Amphihevir is a potent, selective HCV NS4B inhibitor with EC50 of 0.34 and 1.97 nM against the GT1a (H77) and GT1b replicon in luciferase assays.
PC-72892

Dichlorcyclizine

HCV entry inhibitor

Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection with EC50 of 9.92 and 4.53 uM, respectively.
PC-72891

Fluoxazolevir

HCV entry inhibitor

Fluoxazolevir (NCGC00351982) is a potent, small molecule entry inhibitor of HCV with EC50 of 18.8 nM.
PC-72626

AT-527

HCV inhibitor

AT-527 (AT527, Bemnifosbuvir hemisulfate, RG-6422) is a novel phosphoramidate prodrug of AT-511 that has potent in vitro activity against HCV (EC50=5-28 nM), also inhibits replication of SARS-CoV-2 with EC90 of 0.47 uM.
PC-72397

GSK2818713

HCV NS5A inhibitor

GSK2818713 (GSK-2818713) is a nonstructural protein 5A (NS5A) HCV inhibitor with broad genotype coverage.
PC-35585

Cyclophilin inhibitor C31

Cyclophilin inhibitor, HCV inhibitor

Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction.
PC-35444

Coblopasvir

HCV NS5A inhibitor

Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection.
PC-35056

Ciluprevir

HCV NS3/4A inhibitor

Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively.
PC-35032

BI-1388

HCV NS3 protease inhibitor

BI-1388 is a potent, specific, macrocyclic inhibitor of HCV NS3 protease, inhibits viral replication for various HCV genotypes and for resistant mutants D168V and R155K.
PC-63573

MK-3281

HCV NS5B inhibitor

MK-3281 is a potent and orally bioavailable inhibitor of HCV NS5B polymerase with IC50 of 6 nM.
PC-63571

Beclabuvir

HCV NS5B inhibitor

Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively.

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