| Cat. No. |
Product Name |
Information |
| PC-24071 |
ML283
HCV NS3 helicase inhibitor
|
ML283 is a potent, specific inhibitor of HCV non-structural protein 3 (NS3) helicase with IC50 of 2.6 uM (HCV genotype 1b), also inhibits DENV NS3-catalyzed RNA unwinding, also is a potent SARS-CoV-2 nsp13 helicase inhibitor. |
| PC-23934 |
Furaprevir
HCV NS3/4A inhibitor
|
Furaprevir (TG-2349) is a potent, highly selective hepatitis C virus NS3/4A protease inhibitor. |
| PC-22913 |
Coblopasvir dihydrochloride
HCV NS5A inhibitor
|
Coblopasvir (KW136, KW-136) dihydrochloride is a novel HCV NS5A inhibitor under development for treatment of HCV infection. |
| PC-21356 |
Sofosbuvir
HCV NS5B inhibitor
|
Sofosbuvir (GS-7977, PSI-7977) is a prodrug of 2'-F-2'-C-methyluridine monophosphate and HCV NS5B polymerase inhibitor, is active against GT 1a, 1b, and 2a (strain JFH-1) replicons and chimeric replicons containing GT 2a (strain J6), 2b, and 3a NS5B polymerase. |
| PC-21355 |
Dasabuvir
HCV NS5B inhibitor
|
Dasabuvir (ABT-333) is a potent, selective, and nonnucleoside inhibitor of HCV NS5B polymerase with IC50 of 2.2-10.7 nM for HCV genotype 1a and 1b. |
| PC-21353 |
Elbasvir
HCV NS5A inhibitor
|
Elbasvir (MK-8742) is a potent, tetracyclic indole-based HCV NS5A inhibitor, shows broad HCV genotype activity with IC50 of 0.003, 0.003, 0.004, 0.5, 2.4 nM for genotype 1b, 2a, 1a, 1aL31V and 1aY93H, respectively. |
| PC-21352 |
Ombitasvir
HCV NS5A inhibitor
|
Ombitasvir (ABT-267) is a potent, selective pan-genotypic inhibitor of HCV NS5A with EC50 of 1.7-19.3 pM against GT1a, -1b, -2a, -2b, -3a, -4a, and -5a and 366 pM against GT6a. |
| PC-63572 |
Beclabuvir hydrochloride
|
Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively. |
| PC-45986 |
Nucleoside-Analog-2
|
A 4′-azidocytidine analogue that shows anti-HCV activity.. |
