| Cat. No. |
Product Name |
Information |
| PC-63558 |
BI 207524
HCV NS5B inhibitor
|
BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM. |
| PC-43491 |
Anguizole
HCV NS4B inhibitor
|
Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM. |
| PC-63398 |
Sovaprevir
HCV NS3/4A inhibitor
|
Sovaprevir (ACH-1625, ACH-0141625) is a potent HCV NS3/4A inhibitor in development for the treatment of hepatitis C. |
| PC-63397 |
Odalasvir
HCV NS5A inhibitor
|
Odalasvir (ACH-3102, JNJ-64289901) is a potent, second-generation HCV NS5A inhibitor in development for the treatment of hepatitis C. |
| PC-63396 |
GSK-2336805
HCV NS5A inhibitor
|
GSK-2336805 (JNJ-56914845) is a novel potent HCV NS5A inhibitor with multigenotype activity, has EC50s of 58.5, 7.4, and 53.8 pM on genotype 1a (H77), genotype 1b (Con-1 ET), and genotype 2a (JFH-1) replicon cells. |
| PC-63383 |
GSK-2878175
HCV NS5B inhibitor
|
GSK-2878175 (GSK8175, GSK-175, GSK-175A) is a potent, pan-genotypic, second generation HCV NS5B palm polymerase inhibitor with EC50 of 0.4-9.7 nM. |
| PC-63367 |
MK-6169
HCV NS5A inhibitor
|
MK-6169 is a potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 1-33 nM, retains potency against common resistance-associated substitutions in the major genotypes. |
| PC-63304 |
MK-8325 dihydrochloride
HCV NS5A inhibitor
|
MK-8325 dihydrochloride is a potent, selective pan-genotype HCV NS5A inhibitor with IC50 of 15, 1 and 3 pM for GT1a, GT1b and GT2a, respectively. |
| PC-63303 |
MK-8325
HCV NS5A inhibitor
|
MK-8325 is a potent, selective pan-genotype HCV NS5A inhibitor with IC50 of 15, 1 and 3 pM for GT1a, GT1b and GT2a, respectively. |
| PC-43117 |
Paritaprevir
HCV NS3/4A inhibitor
|
Paritaprevir (ABT-450, Veruprevir) is a potent HCV NS3/4A protease inhibitor with EC50 of 1 and 0.21 nM for HCV GT 1a and 1b, respectively. |
| PC-43099 |
Velpatasvir
HCV NS5A inhibitor
|
Velpatasvir (GS-5816) is a second generation, pan-genotypic inhibitor of HCV NS5A, demonstrates a high barrier to resistance in HCV replicon assays.. |
| PC-63073 |
Pibrentasvir
HCV NS5A inhibitor
|
Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6. |
