BI 207524 | HCV NS5B inhibitor | Probechem Biochemicals

Chemical Structure : BI 207524

Catalog No.: PC-63558Not For Human Use, Lab Use Only.

BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.

M.Wt	642.153
Formula	C35H36ClN5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-{4-[(1-{[2-(5-Chloropyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carbonyl]-amino}-cyclobutanecarbonyl)-amino]-2-ethoxy-phenyl}-acrylic acid

1. Beaulieu PL, et al. J Med Chem. 2014 Dec 11;57(23):10130-43.

2. Beaulieu PL, et al. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1135-9.

3. Beaulieu PL, et al. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1140-5.