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SBFI-26 (SBFI26) is a small molecule inhibitor of epidermal- and brain-specific FABP5 and FABP7 that effectively increases anandamide signaling.


A potent, selective, cell-permeable and orally active inhibitor of FABP4 (Fatty acid binding protein 4) with Ki of < 2 nM.

FABP4/5 inhibitor compound 3

FABP4/5 inhibitor compound 3 is a potent dual FABP4 and FABP5 inhibitor with Kd of 0.02 and 0.56 uM, respectively.

FABP4/5 inhibitor compound 2

FABP4/5 inhibitor compound 2 is a potent dual FABP4 and FABP5 inhibitor with Kd of 0.01 and 0.52 uM, respectively, reduces isoproterenol-stimulated lipolysis in mouse 3T3-L1 adipocytes with IC50 of 22 uM.

FABP4 inhibitor 1

A potent, selective FABP4 inhibitor with Ki of 30 nM..

HTS 01037

HTS01037 is a highly potent ligand of adipocyte fatty acid binding protein (A-FABP/aP2) with Ki of 0.67 uM.

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