| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-60477 |
TAK-441
|
1186231-83-3 |
A highly potent, orally active hedgehog signaling (Hh) inhibitor with IC50 of 4.4 nM in Gli-luc reporter assays. |
| PC-70165 |
RUSKI-201
|
1458031-48-5 |
A potent, selective and cell active Hedgehog acyltransferase (Hhat) inhibitor with IC50 of 0.87 uM. |
| PC-45464 |
RU-SKI 43 hydrochloride
|
|
A small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM. |
| PC-45463 |
RU-SKI 43
|
1043797-53-0 |
A small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM. |
| PC-42258 |
Ciliobrevin A
|
302803-72-1 |
A small molecule Hedgehog pathway inhibitor (IC50=7 uM) that acts downstream of Su(fu) to modulate Gli processing, activation or trafficking. |
| PC-45147 |
Cyclopamine
|
4449-51-8 |
A natural steroidal alkaloid that inhibits hedgehog (Hh) signaling with IC50 of 46 nM. |
| PC-49551 |
Picoberin
|
2581063-99-0 |
Picoberin is a highly potent (low picomolar) inhibitor of purmorphamine- and Sonic Hedgehog (Shh)-induced osteogenesis with IC50 of 3 pM, acts as an AhR agonist and induces the expression of AhR target genes, thereby suppressing osteoblast differentiation. |
