BRD9526 |CAS:1446352-30-2 Probechem Biochemicals

Chemical Structure : BRD9526

BRD9526 (BRD 9526)

Catalog No.: PC-62852Not For Human Use, Lab Use Only.

BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM, partially lowers Gli1 expression at concentrations of 10 uM, a useful probe of Shh signaling pathway. .

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Biological Activity

BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM, partially lowers Gli1 expression at concentrations of 10 uM, a useful probe of Shh signaling pathway.

Physicochemical Properties

M.Wt	584.509
Formula	C26H31Cl2N3O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Cyclopropanecarboxamide, N-[(2R,3S)-2-[[[(2,4-dichlorophenyl)sulfonyl]methylamino]methyl]-3,4,5,6-tetrahydro-5-[(1R)-2-hydroxy-1-methylethyl]-3-methyl-6-oxo-2H-1,5-benzoxazocin-10-yl]-

References

1. Schaefer GI, et al. J Am Chem Soc. 2013 Jul 3;135(26):9675-80.

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BRD9526 (BRD 9526)

Biological Activity

Physicochemical Properties

References

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