| Cat. No. |
Product Name |
Information |
| PC-49040 |
HhAg1.5
|
HhAg1.5 (SAg1.5) is a small molecule Hedgehog agonist with EC50 of 1 nM, induces cilia translocation of SMO and GLI transcription factor activation, efficiently generates expandable liver stem cells (LSCs) in vitro. |
| PC-49012 |
MDB5
|
MDB5 is a potent hedgehog (Hh) signaling pathway inhibitor, exhibits stronger inhibition of the Hh pathway and anticancer effect in vitro and vivo than GDC-0449. |
| PC-72867 |
Rhonin
|
Rhonin is the first small-molecule ligand of the RHO GDP-dissociation inhibitor 1 (RHOGDI1), binds to RHOGDI (Ki=2.2 uM), is an inhibitor of Hh-induced osteogenesis. |
| PC-60477 |
TAK-441
|
A highly potent, orally active hedgehog signaling (Hh) inhibitor with IC50 of 4.4 nM in Gli-luc reporter assays. |
| PC-70165 |
RUSKI-201
|
RUSKI-201 is a potent, selective and cell active Hedgehog acyltransferase (Hhat) inhibitor with IC50 of 0.87 uM. |
| PC-45464 |
RU-SKI 43 hydrochloride
|
A small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM. |
| PC-45463 |
RU-SKI 43
|
A small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM. |
