Cat. No. |
Product Name |
Information |
PC-62176 |
AY9944
DHCR7 inhibitor
|
AY9944 is a cholesterol biosynthesis inhibitor that targets the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM), attenuates of Smoothened-dependent and -independent Hh signaling. |
PC-60477 |
TAK-441
Hedgehog inhibitor
|
TAK-441 is a highly potent, orally active hedgehog signaling (Hh) inhibitor with IC50 of 4.4 nM in Gli-luc reporter assays. |
PC-70165 |
RUSKI-201
HHAT inhibitor
|
RUSKI-201 is a potent, selective and cell active Hedgehog acyltransferase (Hhat) inhibitor with IC50 of 0.87 uM. |
PC-45464 |
RU-SKI 43 hydrochloride
Hedgehog acyltransferase inhibitor
|
RU-SKI 43 hydrochloride is a small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM. |
PC-45463 |
RU-SKI 43
Hedgehog acyltransferase inhibitor
|
RU-SKI 43 is a small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM. |
PC-45147 |
Cyclopamine
Hedgehog inhibitor
|
Cyclopamine is a natural steroidal alkaloid that inhibits hedgehog (Hh) signaling with IC50 of 46 nM. |