Catalog No.: PC-62176Not For Human Use, Lab Use Only.
AY9944 is a cholesterol biosynthesis inhibitor that targets the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM), attenuates of Smoothened-dependent and -independent Hh signaling.
AY9944 is a cholesterol biosynthesis inhibitor that targets the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM), attenuates of Smoothened-dependent and -independent Hh signaling.
AY9944 has been used to recapitulate phenotypes of Smith-Lemli-Opitz syndrome in animal model.
