| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38811 |
7HP349
|
1378535-08-0 |
Alintegimod (7HP349) is a small molecule activator of the integrins αLβ2 (LFA-1) and α4β1 (VLA-4). 7HP349 directly activates integrin cell adhesion receptors crucial for the generation of an immune response. |
| PC-72987 |
ADH-503
|
2055362-72-4 |
ADH-503 (GB1275, Leukadherin-1 choline) is a small-molecule allosteric agonist of CD11b that can render tumors more sensitive to checkpoint blockade. |
| PC-35657 |
AJM300
|
401905-67-7 |
AJM300 (Carotegrast methyl, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis.. |
| PC-35165 |
ALG1001
|
1307293-62-4 |
ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis. |
| PC-62001 |
MK-0429
|
227963-15-7 |
MK-0429 is a potent, selective, orally-active nonpeptide αvβ3 integrin inhibitor with IC50 of 0.08 nM in SPAV3 assay. |
| PC-61300 |
BIO-5192
|
327613-57-0 |
BIO-5192 is a potent, highly selective inhibitor of integrin α4β1 (VLA-4) with Kd of <10 pM, IC50 of 1.8 nM. |
| PC-61261 |
TBC3486
|
247044-77-5 |
TBC3486 is a potent, selective, non-peptidic integrin α4β1 (VLA-4) antagonist with IC50 of 9 nM, displays 200-fold selectivity over α4β7 (IC50=2.1 uM). |
