| Cat. No. |
Product Name |
Information |
| PC-28520 |
Ventegatide
Integrin-binding peptide
|
Ventegatide is a 23-amino acid integrin-binding peptide via the RGD sequence, promotes osteoblast and chondroblast differentiation, induces articular cartilage formation in vitro and in vivo. |
| PC-27931 |
GRGDSP
RGD peptide, Integrin inhibitor
|
GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic hexapeptide containing the tripeptide Arg-Gly-Asp (RGD), is an integrin inhibitor and can inhibit tumor cell-adhesion to endothelial cells, significantly inhibits the proliferative response of TNCB-immune T cells in vitro. |
| PC-27662 |
AJM347
α4β7 integrin antagonist
|
AJM347 is a potent, selective and orally active α4β7 integrin antagonist, inhibits the binding of immune cells expressing α4β7 integrin to gastrointestinal submucosa, while not interacting with cells expressing α4β1 integrin. |
| PC-27517 |
Zotemtegrast
α4β7 integrin inhibitor
|
Zotemtegrast (LY4268989, MORF-057) is a selecitve, orally bioavailable of alpha4beta7 integrin (α4β7 integrin), inhibits α4β7 integrin-mediated recruitment of α4β7-expressing lymphocytes to the gut. |
| PC-25047 |
GS-1069518
α4β7 integrin inhibitor
|
GS-1069518 is a potent and selective α4β7 integrin inhibitor. |
| PC-25046 |
Emvistegrast
α4β7 integrin inhibitor
|
Emvistegrast (GS-1427) is an oral prodrug that is rapidly converted to the active species GS-1069518, a potent and selective α4β7 integrin inhibitor. |
| PC-23935 |
Integrin α5β1 inhibitor MRT1
Integrin α5β1 inhibitor
|
Integrin α5β1 inhibitor MRT1 is a specific small molecule inhibitor of RGD (arginylglycylaspartic acid)-binding integrin α5β1 with IC50 of 40 nM in fluorescence polarization assays, and IC50 of 18 and 54 nM for other RGD binding β1 integrins αvβ1 and α8β1. |
| PC-23275 |
MORF-627
αvβ6 integrin inhibitor
|
MORF-627 is a highly selective inhibitor of integrin αvβ6 with IC50 of 1.1 nM, >300-fold selective over αvβ1 and αvβ8. |
| PC-23193 |
Carotegrast
α4 integrin inhibitor
|
Carotegrast (HCA2969) is a potent, selective, orally available alpha 4 integrin (α4 integrin) antagonist with KD/ IC50 of 0.32/5.8 nM, 0.46 nM/1.4 nM, and 0.2/26 nM for human integrin α4β1, human α4β7 and mouse α4β7 respectively. |
| PC-21536 |
ATN-161 TFA salt
Integrin α5β1/αvβ3 inhibitor
|
ATN-161 TFA salt (Ac-PHSCN-NH2) is a small peptide inhibitor of integrin alpha5 beta1 (α5β1) and alphavbeta3 (αvβ3) with binding Kd of 1.0 and 0.6 uM, respectively, inhibits breast cancer growth and metastasis. |
| PC-21535 |
ATN-161
Integrin α5β1/αvβ3 inhibitor
|
ATN-161 (Ac-PHSCN-NH2) is a small peptide inhibitor of integrin alpha5 beta1 (α5β1) and alphavbeta3 (αvβ3) with binding Kd of 1.0 and 0.6 uM, respectively, inhibits breast cancer growth and metastasis. |
| PC-20146 |
E7820
Integrin α2 inhibitor
|
E7820 (E-7820) is a unique, oral sulfonamide derivative angiogenesis inhibitor, inhibits integrin α2 (ITGA2) mRNA expression and suppresses tube formation through the suppression of integrin alpha2. |
