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Request The Product List ofIntegrin Integrin

Cat. No. Product Name CAS No. Information
PC-38811

7HP349

1378535-08-0 Alintegimod (7HP349) is a small molecule activator of the integrins αLβ2 (LFA-1) and α4β1 (VLA-4). 7HP349 directly activates integrin cell adhesion receptors crucial for the generation of an immune response.
PC-72987

ADH-503

2055362-72-4 ADH-503 (GB1275, Leukadherin-1 choline) is a small-molecule allosteric agonist of CD11b that can render tumors more sensitive to checkpoint blockade.
PC-35657

AJM300

401905-67-7 AJM300 (Carotegrast methyl, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis..
PC-35165

ALG1001

1307293-62-4 ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.
PC-62001

MK-0429

227963-15-7 MK-0429 is a potent, selective, orally-active nonpeptide αvβ3 integrin inhibitor with IC50 of 0.08 nM in SPAV3 assay.
PC-61300

BIO-5192

327613-57-0 BIO-5192 is a potent, highly selective inhibitor of integrin α4β1 (VLA-4) with Kd of <10 pM, IC50 of 1.8 nM.
PC-61261

TBC3486

247044-77-5 TBC3486 is a potent, selective, non-peptidic integrin α4β1 (VLA-4) antagonist with IC50 of 9 nM, displays 200-fold selectivity over α4β7 (IC50=2.1 uM).

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