TBC4746 | VLA-4 inhibitor | Probechem Biochemicals

Chemical Structure : TBC4746

TBC4746 (AVA4746)

Catalog No.: PC-49346Not For Human Use, Lab Use Only.

TBC 4746 (AVA4746) is a small molecule mimetic of VCAM-1 that binds VLA-4 on B-ALL cells with high affinity and efficiently blocks ligand-binding with VCAM-1 with EC50 of 38.52 nM.

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Biological Activity

TBC 4746 (AVA4746) is a small molecule mimetic of VCAM-1 that binds VLA-4 on B-ALL cells with high affinity and efficiently blocks ligand-binding with VCAM-1 with EC50 of 38.52 nM.

Physicochemical Properties

M.Wt	469.922
Formula	C24H24ClN3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S)-3-(((1-(2-Chlorobenzyl)-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3yl)amino)carbonyl)amino-3-(4-methylphenyl)propanoic acid

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TBC4746 (AVA4746)

Biological Activity

Physicochemical Properties

References

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